Title : The arachidonic acid-LTB4-BLT2 pathway enhances human B-CLL aggressiveness.

Pub. Date : 2014 Nov

PMID : 25072959






1 Functional Relationships(s)
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1 Our results showed that aggressive B-CLL tumor cells, i.e. cells with an annual proliferation index above 2, over-expressed calcium-dependent and calcium-independent phospholipases A2 (cPLA2-alpha and iPLA2-beta, respectively), 5-lipoxygenase (5LOX) and leukotriene A4 hydroxylase (LTA4H). Calcium phospholipase A2 group VI Homo sapiens