Guanosine Diphosphate

Rho GDP dissociation inhibitor alpha ; Homo sapiens







47 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35170181 The Pseudo-Natural Product Rhonin Targets RHOGDI. 2022 Apr 25 1
2 33913706 A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases. 2021 May 18 1
3 24598074 Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task. 2014 1
4 23283986 αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion. 2013 Feb 1
5 23406297 ARHGDIA, a mutant TP53-associated Rho GDP dissociation inhibitor, is over-expressed in gene expression profiles of TP53 disrupted chronic lymphocytic leukaemia cells. 2013 May 1
6 23918979 Negative charges in the flexible N-terminal domain of Rho GDP-dissociation inhibitors (RhoGDIs) regulate the targeting of the RhoGDI-Rac1 complex to membranes. 2013 Sep 1 1
7 22628549 Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI. 2012 Aug 3 2
8 20127689 Protein-protein-interactions in a multiplexed, miniaturized format a functional analysis of Rho GTPase activation and inhibition. 2010 Apr 1
9 19581296 New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes. 2009 Aug 28 4
10 18505730 Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP. 2008 Aug 8 3
11 17909265 Rho GDP dissociation inhibitor alpha interacts with estrogen receptor alpha and influences estrogen responsiveness. 2007 Oct 1
12 16702219 Liposomes comprising anionic but not neutral phospholipids cause dissociation of Rac(1 or 2) x RhoGDI complexes and support amphiphile-independent NADPH oxidase activation by such complexes. 2006 Jul 14 5
13 15513926 Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors. 2005 Feb 11 2
14 15292224 ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor. 2004 Oct 8 2
15 12198156 Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI. 2002 Sep 2 2
16 11114252 Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI. 2001 Jan 5 4
17 11285260 Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP. 2001 Jun 15 2
18 11298742 Structural consequences of site-directed mutagenesis in flexible protein domains: NMR characterization of the L(55,56)S mutant of RhoGDI. 2001 Apr 1
19 11368848 Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI). 2001 May 1
20 11375519 Crystallization and preliminary crystallographic studies of RhoGDI in complex with the radixin FERM domain. 2001 Jun 2
21 11513579 Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex. 2001 Aug 28 4
22 10655614 The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI. 2000 Feb 1
23 10673424 Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1. 2000 Jan 15 1
24 10698706 GDP dissociation inhibitor D4-GDI (Rho-GDI 2), but not the homologous rho-GDI 1, is cleaved by caspase-3 during drug-induced apoptosis. 2000 Mar 15 1
25 10779444 Differential expression and regulation of GTPases (RhoA and Rac2) and GDIs (LyGDI and RhoGDI) in neutrophils from patients with severe congenital neutropenia. 2000 May 1 2
26 10411652 Phosphoinositide-dependent activation of Rho A involves partial opening of the RhoA/Rho-GDI complex. 1999 Jun 3
27 10433515 Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. 1999 Aug 1
28 9422735 The small GTP-binding protein Rac promotes the dissociation of gelsolin from actin filaments in neutrophils. 1998 Jan 9 1
29 9242378 Association of the Rho family small GTP-binding proteins with Rho GDP dissociation inhibitor (Rho GDI) in Saccharomyces cerevisiae. 1997 Jul 24 2
30 9287351 Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. 1997 Sep 12 1
31 7592961 RhoA and a cytosolic 50-kDa factor reconstitute GTP gamma S-dependent phospholipase D activity in human neutrophil subcellular fractions. 1995 Nov 10 1
32 7708758 A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors. 1995 Mar 28 1
33 7852400 Low molecular weight GTP-binding proteins in HL-60 granulocytes. Assessment of the role of ARF and of a 50-kDa cytosolic protein in phospholipase D activation. 1995 Feb 17 1
34 8139548 rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells. 1994 Apr 1
35 8141770 Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane. 1994 Mar 15 1
36 8226937 Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21. 1993 Nov 15 6
37 8253741 Biologically active lipids are regulators of Rac.GDI complexation. 1993 Dec 15 1
38 8352776 The nucleotide exchange rates of rho and rac small GTP-binding proteins are enhanced to different extents by their regulatory protein Smg GDS. 1993 Aug 16 1
39 8356058 Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. 1993 Aug 15 1
40 8419353 GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. 1993 Jan 15 1
41 8491184 A novel role for RhoGDI as an inhibitor of GAP proteins. 1993 May 1
42 1316893 Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins. 1992 May 25 2
43 1429634 The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein. 1992 Nov 15 1
44 1464587 Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase. 1992 Dec 25 1
45 1517204 The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins. 1992 Sep 5 1
46 1634508 Functional interactions of stimulatory and inhibitory GDP/GTP exchange proteins and their common substrate small GTP-binding protein. 1992 Jul 25 5
47 1734890 Both stimulatory and inhibitory GDP/GTP exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins. 1992 Jan 31 1