Title : GDP dissociation inhibitor D4-GDI (Rho-GDI 2), but not the homologous rho-GDI 1, is cleaved by caspase-3 during drug-induced apoptosis.

Pub. Date : 2000 Mar 15

PMID : 10698706






1 Functional Relationships(s)
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1 Our results strongly suggest the differential regulation of the homologous GDP dissociation inhibitors Rho-GDI 1 and D4-GDI during drug-induced apoptosis by proteolysis mediated by caspase-3 but not by caspase-1. Guanosine Diphosphate Rho GDP dissociation inhibitor alpha Homo sapiens