Title : Structural consequences of site-directed mutagenesis in flexible protein domains: NMR characterization of the L(55,56)S mutant of RhoGDI.

Pub. Date : 2001 Apr

PMID : 11298742






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The guanine dissociation inhibitor RhoGDI consists of a folded C-terminal domain and a highly flexible N-terminal region, both of which are essential for biological activity, that is, inhibition of GDP dissociation from Rho GTPases, and regulation of their partitioning between membrane and cytosol. Guanosine Diphosphate Rho GDP dissociation inhibitor alpha Homo sapiens