Arsenic Trioxide

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







20 Article(s)
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1 33070465 AMP-activated protein kinase activation primes cytoplasmic translocation and autophagic degradation of the BCR-ABL protein in CML cells. 2021 Jan 1
2 32305283 Arsenic trioxide-induced p38 MAPK and Akt mediated MCL1 downregulation causes apoptosis of BCR-ABL1-positive leukemia cells. 2020 Apr 17 5
3 24129092 VEGF depletion enhances bcr-abl-specific sensitivity of arsenic trioxide in chronic myelogenous leukemia. 2013 Nov 3
4 22330069 Inhibition of small GTPase RalA regulates growth and arsenic-induced apoptosis in chronic myeloid leukemia (CML) cells. 2012 Jun 1
5 22898604 Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide. 2012 Oct 25 1
6 23100300 BCR-ABL/p62/SQSTM1: a cannibal embrace. 2012 Oct 25 2
7 21570118 AID expression is correlated with Bcr-Abl expression in CML-LBC and can be down-regulated by As2O3 and/or imatinib. 2011 Oct 1
8 19563028 [Arsenic trioxide inhibits cell growth in imatinib-resistant bcr-abl mutant cell lines in vitro]. 2009 Jan 6
9 17495969 Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta. 2007 Jul 2
10 17550858 Enhanced Bcr-Abl-specific antileukemic activity of arsenic trioxide (Trisenox) through glutathione-depletion in imatinib-resistant cells. 2007 Jun 4
11 17121903 Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation. 2006 Nov 15 1
12 17121928 Activation of mammalian target of rapamycin and the p70 S6 kinase by arsenic trioxide in BCR-ABL-expressing cells. 2006 Nov 1
13 14534537 Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis. 2003 Oct 9 1
14 14633726 Arsenic trioxide inhibits translation of mRNA of bcr-abl, resulting in attenuation of Bcr-Abl levels and apoptosis of human leukemia cells. 2003 Nov 15 4
15 12135670 In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia. 2002 Jul 4
16 12476305 Novel targeted therapies for Bcr-Abl positive acute leukemias: beyond STI571. 2002 Dec 9 1
17 11368438 Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cells. 2001 May 6
18 10910048 BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity. 2000 Jul 1 7
19 11721366 [Effects of As2O3 on the BCR/ABL protein tyrosine phosphorylation in K562 cells]. 1999 Dec 5
20 11243118 [Protein tyrosine kinase (PTK) activities during the induction of apoptosis by arsenic trioxide (As2O3)]. 1998 May 3