Title : Novel targeted therapies for Bcr-Abl positive acute leukemias: beyond STI571.

Pub. Date : 2002 Dec 9

PMID : 12476305






1 Functional Relationships(s)
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1 Small molecule inhibitors that downregulate the levels of Bcr-Abl by inhibiting its translation, e.g., arsenic trioxide, or promoting its proteasomal degradation, e.g., geldanamycin analogues, have also been identified. Arsenic Trioxide ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens