274 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
251 | 17538248 | Imatinib and nilotinib induce apoptosis of chronic myeloid leukemia cells through a Bim-dependant pathway modulated by cytokines. | 2007 Jun | 2 |
252 | 17613767 | The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines. | 2007 Jul | 2 |
253 | 17642017 | Drug evaluation: Nilotinib - a novel Bcr-Abl tyrosine kinase inhibitor for the treatment of chronic myelocytic leukemia and beyond. | 2007 Jul | 2 |
254 | 17701954 | Tyrosine kinase inhibitors for the treatment of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. | 2007 Sep 15 | 1 |
255 | 17715389 | Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. | 2007 Nov 15 | 6 |
256 | 17720881 | Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. | 2007 Dec 1 | 2 |
257 | 17785585 | Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors. | 2007 Dec 1 | 1 |
258 | 17853901 | Flying under the radar: the new wave of BCR-ABL inhibitors. | 2007 Oct | 2 |
259 | 17964980 | [Treatment of chronic myeloid leukemia in 2007]. | 2007 Oct | 1 |
260 | 17964981 | [Acute lymphoblastic leukemia with Philadelphia chromosome: treatment with kinase inhibitors]. | 2007 Oct | 1 |
261 | 17987222 | Nilotinib therapy in chronic myelogenous leukemia. | 2007 Oct | 1 |
262 | 18067005 | Strategies for overcoming imatinib resistance in chronic myeloid leukemia. | 2007 Dec | 1 |
263 | 19707322 | Nilotinib: a novel encouraging therapeutic option for chronic myeloid leukemia patients with imatinib resistance or intolerance. | 2007 Jun | 1 |
264 | 16537804 | Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl-expressing human leukemia cells. | 2006 Jul 15 | 2 |
265 | 16597591 | OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. | 2006 Jul 15 | 1 |
266 | 16614241 | Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107). | 2006 Aug 15 | 3 |
267 | 16721371 | AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL. | 2006 Jun 19 | 4 |
268 | 16772610 | Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations. | 2006 Oct 1 | 4 |
269 | 17106016 | Novel treatment strategies for chronic myeloid leukemia. | 2006 Dec 1 | 1 |
270 | 17124064 | Defining and managing imatinib resistance. | 2006 | 1 |
271 | 18221045 | Second generation Abl kinase inhibitors and novel compounds to eliminate the Bcr-Abl/T315I clone. | 2006 Nov | 1 |
272 | 15930265 | In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. | 2005 Jun 1 | 2 |
273 | 16000593 | AMN107, a novel aminopyrimidine inhibitor of Bcr-Abl, has in vitro activity against imatinib-resistant chronic myeloid leukemia. | 2005 Jul 1 | 3 |
274 | 16078266 | AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells. | 2005 Sep 15 | 1 |