Pub. Date : 2004 Jun 4
PMID : 15007073
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A holo-G protein with a high affinity Galpha C terminus shows a specific change of the reaction rate in the GDP release and GTP uptake steps of catalysis. | Guanosine Diphosphate | succinate-CoA ligase GDP/ADP-forming subunit alpha | Homo sapiens |
| 2 | We interpret the data by a sequential fit model where (i) the initial encounter between R* and the G protein occurs with the Gbetagamma subunit, and (ii) the Galpha C-terminal tail then interacts with R* to release bound GDP, thereby decreasing the affinity of R* for the Gbetagamma subunit. | Guanosine Diphosphate | succinate-CoA ligase GDP/ADP-forming subunit alpha | Homo sapiens |