Iron

hemojuvelin BMP co-receptor ; Homo sapiens







106 Article(s)
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51 21873547 TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals. 2011 Oct 20 2
52 21901658 The molecular pathogenesis of hereditary hemochromatosis. 2011 Aug 1
53 20593054 Homozygous G320V mutation in the HJV gene causing juvenile hereditary haemochromatosis type A. A case report. 2010 Jun 1
54 20713458 Immunoassay for human serum hemojuvelin. 2010 Dec 3
55 20880062 Iron state in association with retinoid metabolism in non-alcoholic fatty liver disease. 2010 Dec 1
56 20937842 Matriptase-2- and proprotein convertase-cleaved forms of hemojuvelin have different roles in the down-regulation of hepcidin expression. 2010 Dec 10 2
57 21054916 Molecular basis of iron-loading disorders. 2010 Nov 8 1
58 22043450 Control of systemic iron homeostasis by the hemojuvelin-hepcidin axis. 2010 Nov 3
59 18952085 Suppressive effects of retinoids on iron-induced oxidative stress in the liver. 2009 Jan 1
60 19029439 Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells. 2009 Feb 19 3
61 19287179 Hemojuvelin: the hepcidin story continues. 2009 6
62 19306018 Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism. 2009 Jun 6
63 19698085 Molecular biology, genetics and biochemistry of the repulsive guidance molecule family. 2009 Aug 27 2
64 17869549 Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. 2008 Jan-Feb 3
65 17938254 Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. 2008 Jan 15 2
66 18287331 Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin. 2008 Apr 6
67 18326817 Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. 2008 May 15 2
68 18384687 Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin. 2008 Apr 2 4
69 18421430 A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells. 2008 May 1
70 18469261 Pathways underlying iron accumulation in human nonalcoholic fatty liver disease. 2008 May 3
71 18488871 [Hepcidin--the discovery of a small protein with a pivotal role in iron homeostasis]. 2008 Mar 1
72 18634255 [Novel aspects of pathogenesis of hereditary hemochromatosis]. 2008 Jan 3
73 18725184 A Q312X mutation in the hemojuvelin gene is associated with cardiomyopathy due to juvenile haemochromatosis. 2008 Oct 2
74 18809758 Down-regulation of hepcidin in porphyria cutanea tarda. 2008 Dec 1 2
75 18827264 Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response. 2008 Oct 2
76 17098454 Hepatic iron metabolism gene expression profiles in HFE associated hereditary hemochromatosis. 2007 Jan-Feb 3
77 17194590 Iron uptake and metabolism in the new millennium. 2007 Feb 1
78 17264300 Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. 2007 May 15 4
79 17331953 Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin. 2007 Apr 27 3
80 17473933 The relevance of the intestinal crypt and enterocyte in regulating iron absorption. 2007 Nov 2
81 17521857 [Pathophysiology and genetics of classic HFE (type 1) hemochromatosis]. 2007 Sep 2
82 17540841 Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. 2007 Sep 15 1
83 17607352 Hepcidin regulation: ironing out the details. 2007 Jul 2
84 17607365 Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. 2007 Jul 6
85 18293685 [Hereditary hemochromatosis]. 2007 Jul-Sep 1
86 16604073 Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. 2006 May 3
87 15685557 Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes. 2005 Feb 1
88 15710580 Hemojuvelin (HJV)-associated hemochromatosis: analysis of HJV and HFE mutations and iron overload in three families. 2005 Feb 1
89 15875150 Hemojuvelin: a supposed role in iron metabolism one year after its discovery. 2005 Jul 2
90 15893030 [Molecular basis in hereditary haemochromatosis]. 2005 May 1
91 15998830 Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. 2005 Oct 15 3
92 16075058 Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. 2005 Aug 4
93 16099526 Three patients with middle-age-onset hemochromatosis caused by novel mutations in the hemojuvelin gene. 2005 Oct 1
94 16103117 Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells. 2005 Oct 7 4
95 16103673 Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway. 2005 2
96 16158226 Mechanisms of haem and non-haem iron absorption: lessons from inherited disorders of iron metabolism. 2005 Aug 3
97 14647275 Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. 2004 Jan 2
98 14982873 Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis. 2004 Jun 1 1
99 15254010 The recently identified type 2A juvenile haemochromatosis gene (HJV), a second candidate modifier of the C282Y homozygous phenotype. 2004 Sep 1 1
100 15315789 Juvenile hemochromatosis HJV-related revealed by cardiogenic shock. 2004 Sep-Oct 1