Title : Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway.

Pub. Date : 2005

PMID : 16103673






2 Functional Relationships(s)
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1 METHODS: Using quantitative RT-PCR, the iron-dependent hepatic expression patterns of HAMP, HJV, and TFR2 were evaluated in human and murine HFE-related hemochromatosis. Iron hemojuvelin BMP co-receptor Homo sapiens
2 An HFE-independent pathway that seems to involve TFR2 and HJV can regulate HAMP expression under conditions of iron overload. Iron hemojuvelin BMP co-receptor Homo sapiens