Sphingolipids

sphingosine-1-phosphate receptor 1 ; Mus musculus







110 Article(s)
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51 24448174 TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. 2014 Jun 1
52 25198418 Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model. 2014 2
53 25309325 Fingolimod for the treatment of neurological diseases-state of play and future perspectives. 2014 1
54 25347472 Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. 2014 Dec 5
55 22750505 S1P lyase in skeletal muscle regeneration and satellite cell activation: exposing the hidden lyase. 2013 Jan 1
56 23449739 Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury. 2013 Jul 2
57 23643308 Sphingosine-1-phosphate exhibits anti-proliferative and anti-inflammatory effects in mouse models of psoriasis. 2013 Jul 1
58 23731666 Sphingosine-1-phosphate inhibits ceramide-induced apoptosis during murine preimplantation embryonic development. 2013 Aug 1
59 24265321 A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis. 2013 Dec 27 2
60 24619572 Sphingosine Phosphate Lyase Regulates Murine Embryonic Stem Cell Proliferation and Pluripotency through an S1P2/STAT3 Signaling Pathway. 2013 Jun 24 1
61 24744854 Sphingosine-1-phosphate acts as a key molecule in the direct mediation of renal fibrosis. 2013 Dec 1 1
62 21302134 Sphingosine-1-phosphate attenuates lung injury induced by intestinal ischemia/reperfusion in mice: role of inducible nitric-oxide synthase. 2012 Feb 1
63 22178384 Sphingosine 1-phosphate stimulates proliferation and migration of satellite cells: role of S1P receptors. 2012 Feb 1
64 22234485 Sphingosine kinase inhibition exerts both pro- and anti-atherogenic effects in low-density lipoprotein receptor-deficient (LDL-R(-/-)) mice. 2012 Mar 1
65 22723910 Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. 2012 2
66 22781001 Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. 2012 Sep 1
67 22933630 A sphingosine-1-phosphate receptor 1-directed agonist reduces central nervous system inflammation in a plasmacytoid dendritic cell-dependent manner. 2012 Oct 1 1
68 21173151 Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking. 2011 Mar 4 3
69 21209394 A role of sphingosine kinase 1 in head and neck carcinogenesis. 2011 Mar 1
70 21256191 Redox regulation of ERK1/2 activation induced by sphingosine 1-phosphate in fibroblasts: involvement of NADPH oxidase and platelet-derived growth factor receptor. 2011 Apr 1
71 21292568 Simultaneous determination of sphingosine and sphingosine 1-phosphate in biological samples by liquid chromatography-tandem mass spectrometry. 2011 Mar 1 1
72 21335477 S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart. 2011 May 1
73 21556483 S1P is associated with protection in human and experimental cerebral malaria. 2011 1
74 21712494 Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. 2011 Oct 2
75 22314562 Cardioprotective role of sphingosine-1-phosphate. 2011 Dec 1
76 19556602 Systemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse. 2010 May 1
77 19749179 Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung. 2010 Oct 5
78 20036321 Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia. 2010 Mar 10 1
79 20060809 Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells. 2010 Feb 5 3
80 20061445 Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2. 2010 Apr 1
81 20097939 Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver. 2010 Apr 2 5
82 18824518 Role for sphingosine kinase 1 in colon carcinogenesis. 2009 Feb 1
83 19119317 Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions. 2009 1
84 19276615 Effects of synthetic sphingosine-1-phosphate analogs on cytosolic phospholipase A2alpha-independent release of arachidonic acid and cell toxicity in L929 fibrosarcoma cells: the structure-activity relationship. 2009 Mar 1
85 19285924 Quantitative analysis of sphingosine-1-phosphate by HPLC after napthalene-2,3-dicarboxaldehyde (NDA) derivatization. 2009 Apr 1 1
86 19874715 Sphingosine 1-phosphate induces vascular endothelial growth factor expression in endothelial cells. 2009 Oct 31 1
87 18026195 Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice. 2008 Jan 15 1
88 18058233 Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase. 2008 Apr 1
89 18385762 K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. 2008 Sep 1
90 19017993 Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis. 2008 Dec 1 1
91 17098744 Galpha12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IkappaBalpha. 2007 Jan 19 1
92 17242282 FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice. 2007 Jan 30 1
93 17242884 Regulation and functional roles of sphingosine kinases. 2007 Feb 1
94 17341687 The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. 2007 Jul 1
95 17361098 Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again. 2007 Mar 1 2
96 17449940 Sphingosine 1-phosphate triggers apoptotic signal for B16 melanoma cells via ERK and caspase activation. 2007 Apr 1
97 17610857 A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. 2007 Oct 1 1
98 16510307 Sphingosine 1-phosphate inhibits cell migration in C2C12 myoblasts. 2006 Jan 1
99 16632640 Antitumor activity of sphingosine kinase inhibitors. 2006 Aug 1
100 15707407 The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I. 2005 Mar 1