Sphingolipids

sphingosine-1-phosphate receptor 1 ; Mus musculus







110 Article(s)
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1 33197483 Sphingosine 1-Phosphate Receptor 2 Is Central to Maintaining Epidermal Barrier Homeostasis. 2021 May 1
2 33727061 The S1P2 receptor regulates blood-brain barrier integrity and leukocyte extravasation with implications for neurodegenerative disease. 2021 Jun 1
3 34638955 Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile. 2021 Sep 30 2
4 31455837 SGPL1321 mutation: one main trigger for invasiveness of pediatric alveolar rhabdomyosarcoma. 2020 Aug 1
5 31815756 Apolipoprotein M: new connections with diet, adipose tissue and metabolic syndrome. 2020 Feb 1
6 32202615 Effect of sphingosine-1-phosphate on activation of dormant follicles in murine and human ovarian tissue. 2020 May 15 1
7 32393187 Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence from knockout mice. 2020 May 11 1
8 29572542 Aryl hydrocarbon receptor signaling promotes ORMDL3-dependent generation of sphingosine-1-phosphate by inhibiting sphingosine-1-phosphate lyase. 2019 Oct 1
9 30611767 Sphingosine 1-phosphate-mediated activation of ezrin-radixin-moesin proteins contributes to cytoskeletal remodeling and changes of membrane properties in epithelial otic vesicle progenitors. 2019 Apr 1
10 30963819 Sphk1/S1P/S1PR1 Signaling is Involved in the Development of Autoimmune Thyroiditis in Patients and NOD.H-2h4 Mice. 2019 May 1
11 31110049 FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice. 2019 Jul 1
12 31261859 Sphingosine-1-Phosphate Improves the Biological Features of Mouse Bone Marrow-Derived EPCs Partially through PI3K/AKT/eNOS/NO Pathway. 2019 Jun 29 1
13 31426457 Feeding Stimulates Sphingosine-1-Phosphate Mobilization in Mouse Hypothalamus. 2019 Aug 17 3
14 32038629 Sphingosine-1-Phosphate (S-1P) Promotes Differentiation of Naive Macrophages and Enhances Protective Immunity Against Mycobacterium tuberculosis. 2019 2
15 29055687 Sphingosine kinase 1 in breast cancer. 2018 Jan 1
16 29285771 Endotoxemia rocks sphingolipid metabolism at the blood-brain barrier: An Editorial Highlight for 'Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption' on page 172. 2018 Jan 1
17 29351902 Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis. 2018 Apr 1 2
18 29415945 Validating a Selective S1P1 Receptor Modulator Syl930 for Psoriasis Treatment. 2018 Apr 1 2
19 29479306 Identification of Chloride Channels CLCN3 and CLCN5 Mediating the Excitatory Cl- Currents Activated by Sphingosine-1-Phosphate in Sensory Neurons. 2018 1
20 29523764 ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer. 2018 Jun 1
21 29693558 S1P₄ Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells. 2018 Apr 25 1
22 29703731 Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain. 2018 May 7 4
23 29903770 S1P Stimulates Proliferation by Upregulating CTGF Expression through S1PR2-Mediated YAP Activation. 2018 Oct 1
24 30060257 Elevating Endogenous Sphingosine-1-Phosphate (S1P) Levels Improves Endothelial Function and Ameliorates Atherosclerosis in Low Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice. 2018 Aug 1
25 30367841 Sphingosine 1-phosphate promotes mesenchymal stem cell-mediated cardioprotection against myocardial infarction via ERK1/2-MMP-9 and Akt signaling axis. 2018 Dec 15 1
26 28188805 Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. 2017 May 1
27 28262793 Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage. 2017 Mar 6 3
28 28570482 Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation. 2017 Sep 1
29 29028945 Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis. 2017 Dec 7 1
30 29221156 The protective role of sphingosine-1-phosphate against the action of the vascular disrupting agent combretastatin A-4 3-O-phosphate. 2017 Nov 10 1
31 25900155 Periodontal inflammation and alveolar bone loss induced by Aggregatibacter actinomycetemcomitans is attenuated in sphingosine kinase 1-deficient mice. 2016 Feb 1
32 26414003 Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy. 2016 Jan 1
33 26884643 Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. 2016 1
34 27059959 Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet β-Cell Endoplasmic Reticulum Stress and Proliferation. 2016 Jun 3 1
35 27158676 Endothelial Nogo-B regulates sphingolipid biosynthesis to promote pathological cardiac hypertrophy during chronic pressure overload. 2016 Apr 21 1
36 27612439 Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts. 2016 Dec 1
37 27883090 Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism. 2016 Nov 24 1
38 24965069 Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages. 2015 Jun 1
39 25145931 Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury. 2015 Apr 1
40 25176316 Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody. 2015 Jan 1
41 25385827 Upregulation of ABC transporters contributes to chemoresistance of sphingosine 1-phosphate lyase-deficient fibroblasts. 2015 Jan 2
42 25512083 The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. 2015 Apr 1
43 25801013 SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet. 2015 May 1
44 25831442 Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. 2015 Apr 1
45 25908861 Sphingolipids inhibit vimentin-dependent cell migration. 2015 Jun 1 1
46 25930666 Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody. 2015 Aug 1
47 26082434 Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. 2015 Jun 16 1
48 26324848 Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases. 2015 Dec 1
49 27011900 Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat's in the fire. 2015 Oct 1 2
50 24394822 Sphingolipids in lung growth and repair. 2014 Jan 1