Sodium

sodium channel, nonvoltage-gated 1 alpha ; Mus musculus







108 Article(s)
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1 34537283 Luteolin attenuates lipopolysaccharide-induced acute lung injury/acute respiratory distress syndrome by activating alveolar epithelial sodium channels via cGMP/PI3K pathway. 2022 Jan 10 1
2 34740720 Inflammatory alveolar macrophage-derived microvesicles damage lung epithelial cells and induce lung injury. 2022 Jan 1
3 34870751 Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice. 2022 Feb 4
4 35023666 Apelin-13 Decreases Epithelial Sodium Channel (ENaC) Expression and Activity in Kidney Collecting Duct Cells. 2022 Jan 12 3
5 35053120 Iron Inhibits the Translation and Activity of the Renal Epithelial Sodium Channel. 2022 Jan 12 1
6 35104250 The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice. 2022 Mar 8 2
7 35216518 Atrial Natriuretic Peptide and the Epithelial Sodium Channel Contribute to Spinal Cord Injury-Induced Polyuria in Mice. 2022 May 1
8 35506380 Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone. 2022 Jul 1
9 35512853 Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases. 2022 Jun 1
10 35569011 Rodent models to study sodium retention in experimental nephrotic syndrome. 2022 Jul 2
11 33065235 Endothelial epithelial sodium channel involves in high-fat diet-induced atherosclerosis in low-density lipoprotein receptor-deficient mice. 2021 Jan 1 1
12 33258401 Acid-sensing ion channel 3: An analgesic target. 2021 Dec 1
13 33410279 ENaC expression correlates with the acute furosemide-induced K+ excretion. 2021 Jan 1
14 33577799 Inhibition of the epithelial sodium channel (ENaC) by connexin 30 involves stimulation of clathrin-mediated endocytosis. 2021 Jan-Jun 2
15 33650216 Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice. 2021 May 2
16 33713776 Aldosterone alleviates lipopolysaccharide-induced acute lung injury by regulating epithelial sodium channel through PI3K/Akt/SGK1 signaling pathway. 2021 Jun 1
17 33800499 Is the ENaC Dysregulation in CF an Effect of Protein-Lipid Interaction in the Membranes? 2021 Mar 8 1
18 33818128 Deletion of renal Nedd4-2 abolishes the effect of high sodium intake (HS) on Kir4.1, ENaC, and NCC and causes hypokalemia during high HS. 2021 May 1 1
19 33974881 New generation ENaC inhibitors detach cystic fibrosis airway mucus bundles via sodium/hydrogen exchanger inhibition. 2021 Aug 5 2
20 34222246 Homocysteine Causes Endothelial Dysfunction via Inflammatory Factor-Mediated Activation of Epithelial Sodium Channel (ENaC). 2021 2
21 34251271 Critical role of the mineralocorticoid receptor in aldosterone-dependent and aldosterone-independent regulation of ENaC in the distal nephron. 2021 Sep 1 2
22 34272444 Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na+ channel. 2021 Jul 16 2
23 34368091 Conditioned Medium of Bone Marrow Mesenchymal Stem Cells Involved in Acute Lung Injury by Regulating Epithelial Sodium Channels via miR-34c. 2021 2
24 34423678 Experimental nephrotic syndrome leads to proteolytic activation of the epithelial Na+ channel in the mouse kidney. 2021 Oct 1 3
25 34512393 Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs. 2021 2
26 34697091 Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier. 2021 Oct 25 1
27 34863181 Ferulic acid ameliorates lipopolysaccharide-induced tracheal injury via cGMP/PKGII signaling pathway. 2021 Dec 4 1
28 31659629 IL-1 promotes α-epithelial Sodium Channel (α-ENaC) expression in murine lung epithelial cells: involvement of NF-κB. 2020 Sep 2
29 31789848 Mechanisms of sodium retention in nephrotic syndrome. 2020 Mar 3
30 32003683 Mesenchymal Stem Cell-Conditioned Medium Rescues LPS-Impaired ENaC Activity in Mouse Trachea via WNK4 Pathway. 2020 1
31 32009028 Azithromycin Inhibits Constitutive Airway Epithelial Sodium Channel Activation in Vitro and Modulates Downstream Pathogenesis in Vivo. 2020 Apr 1 3
32 32208832 Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice. 2020 Apr 7 2
33 32260115 Sodium Imbalance in Mice Results Primarily in Compensatory Gene Regulatory Responses in Kidney and Colon, but Not in Taste Tissue. 2020 Apr 3 2
34 32299681 Collecting system-specific deletion of Kcnj10 predisposes for thiazide- and low-potassium diet-induced hypokalemia. 2020 Jun 1
35 32442241 Prostaglandin E2 stimulates the epithelial sodium channel (ENaC) in cultured mouse cortical collecting duct cells in an autocrine manner. 2020 Aug 3 3
36 32631918 Scnn1b-Transgenic BALB/c Mice as a Model of Pseudomonas aeruginosa Infections of the Cystic Fibrosis Lung. 2020 Aug 19 2
37 32680508 The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia. 2020 Jul 17 1
38 32817119 Selective Removal of Sodium Salt Taste Disrupts the Maintenance of Dendritic Architecture of Gustatory Relay Neurons in the Mouse Nucleus of the Solitary Tract. 2020 Sep/Oct 2
39 32981895 Cofilin participates in regulating alpha-epithelial sodium channel by interaction with 14-3-3 isoforms. 2020 Jul 30 1
40 33208364 Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models. 2020 Nov 3
41 33308227 Bone marrow mesenchymal stem cells derived miRNA-130b enhances epithelial sodium channel by targeting PTEN. 2020 Dec 11 1
42 30343635 Novel indole and benzothiophene ring derivatives showing differential modulatory activity against human epithelial sodium channel subunits, ENaC β and γ. 2019 Feb 3
43 31006168 Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome. 2019 Dec 1
44 31109455 Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension. 2019 Jul 1 1
45 31222723 Lovastatin attenuates hypertension induced by renal tubule-specific knockout of ATP-binding cassette transporter A1, by inhibiting epithelial sodium channels. 2019 Sep 1
46 31252520 The Absence of Endothelial Sodium Channel α (αENaC) Reduces Renal Ischemia/Reperfusion Injury. 2019 Jun 27 1
47 31570523 Pharmacological reversal of renal cysts from secretion to absorption suggests a potential therapeutic strategy for managing autosomal dominant polycystic kidney disease. 2019 Nov 8 1
48 31617909 Sexual Dimorphism in Obesity-Associated Endothelial ENaC Activity and Stiffening in Mice. 2019 Dec 1 3
49 28861610 Inhibitors of the proteasome stimulate the epithelial sodium channel (ENaC) through SGK1 and mimic the effect of aldosterone. 2018 Feb 1
50 29251736 PGE2 EP1 receptor inhibits vasopressin-dependent water reabsorption and sodium transport in mouse collecting duct. 2018 Mar 1