Pub. Date : 2020 Mar
PMID : 31789848
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent studies from mice, rats and humans have shown that the sodium retention depends on urinary serine proteases and that it can be mitigated by blockers (amiloride, triamterene) of the epithelial sodium channel ENaC. | Sodium | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |
| 2 | Recent studies from mice, rats and humans have shown that the sodium retention depends on urinary serine proteases and that it can be mitigated by blockers (amiloride, triamterene) of the epithelial sodium channel ENaC. | Sodium | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |
| 3 | Experimental and clinical evidence indicate that aberrant proteolytic ENaC activation is a primary driver of sodium retention in nephrotic syndrome and contributes to hypertension in conditions with low-grade proteinuria. | Sodium | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |