| 1 |
34687254 | A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes. | 2022 Mar |
3 |
| 2 |
35620283 | Roxadustat, a Hypoxia-Inducible Factor 1α Activator, Attenuates Both Long- and Short-Term Alcohol-Induced Alcoholic Liver Disease. | 2022 |
1 |
| 3 |
34360999 | CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload. | 2021 Jul 30 |
1 |
| 4 |
34390780 | Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance. | 2021 Oct |
1 |
| 5 |
32053237 | Induction of SIRT1 by melatonin improves alcohol-mediated oxidative liver injury by disrupting the CRBN-YY1-CYP2E1 signaling pathway. | 2020 Apr |
5 |
| 6 |
29637855 | Cytochrome P450s and Alcoholic Liver Disease. | 2018 |
1 |
| 7 |
26278389 | Alcoholic Liver Disease: from CYP2E1 to CYP2A5. | 2017 |
1 |
| 8 |
28103636 | Limited Excessive Voluntary Alcohol Drinking Leads to Liver Dysfunction in Mice. | 2017 Feb |
3 |
| 9 |
28803762 | Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene expression. | 2017 Sep 25 |
1 |
| 10 |
29404441 | The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. | 2017 Dec |
3 |
| 11 |
29404485 | Increased ethanol-inducible cytochrome P450-2E1 and cytochrome P450 isoforms in exosomes of alcohol-exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress. | 2017 Sep |
2 |
| 12 |
26464440 | RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure. | 2016 Feb 18 |
1 |
| 13 |
27216978 | Impact of Dyrk1A level on alcohol metabolism. | 2016 Sep |
1 |
| 14 |
27627966 | Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation. | 2016 Sep 15 |
1 |
| 15 |
28066249 | Development of an IgY Antibody-Based Immunoassay for the Screening of the CYP2E1 Inhibitor/Enhancer from Herbal Medicines. | 2016 |
1 |
| 16 |
29756048 | Alcohol Upregulation of CYP2A5: Role of Reactive Oxygen Species. | 2016 Mar |
9 |
| 17 |
25427906 | Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury. | 2015 |
2 |
| 18 |
25499101 | Circadian rhythms, alcohol and gut interactions. | 2015 Jun |
1 |
| 19 |
25787296 | Hepatoprotective effect of kaempferol against alcoholic liver injury in mice. | 2015 |
1 |
| 20 |
26198575 | Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction. | 2015 Oct |
2 |
| 21 |
24658151 | Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration. | 2014 |
1 |
| 22 |
24891074 | Protective role of CYP2E1 inhibitor diallyl disulfide (DADS) on alcohol-induced malondialdehyde-deoxyguanosine (M1dG) adduct formation. | 2014 Jun |
7 |
| 23 |
25236742 | Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans. | 2014 Dec |
7 |
| 24 |
25454746 | Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction. | 2014 |
3 |
| 25 |
25462064 | Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness. | 2014 |
1 |
| 26 |
22967841 | Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis. | 2013 Jan |
1 |
| 27 |
23023167 | Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol. | 2013 Jul |
9 |
| 28 |
23660503 | Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. | 2013 Jul 15 |
2 |
| 29 |
24064383 | CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. | 2013 Dec |
6 |
| 30 |
22749809 | Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver. | 2012 Sep 1 |
3 |
| 31 |
23241420 | The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them. | 2012 Dec 17 |
1 |
| 32 |
20129692 | TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I. | 2010 Mar |
1 |
| 33 |
20438834 | Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injury. | 2010 Aug 1 |
1 |
| 34 |
20137700 | [Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice]. | 2009 Sep 15 |
2 |
| 35 |
18078827 | CYP2E1 and oxidative liver injury by alcohol. | 2008 Mar 1 |
1 |
| 36 |
18479843 | Supplementing the liquid alcohol diet with chow enhances alcohol intake in C57 BL/6 mice. | 2008 Sep 1 |
1 |
| 37 |
17392391 | Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice. | 2007 Jul |
3 |
| 38 |
17995665 | Protective and alleviative effects from 4 cysteine-containing compounds on ethanol-induced acute liver injury through suppression of oxidation and inflammation. | 2007 Sep |
3 |
| 39 |
16408314 | Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells. | 2006 Feb |
1 |
| 40 |
15576447 | The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity. | 2005 Mar |
1 |
| 41 |
15603755 | Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. | 2005 Jan 6 |
1 |
| 42 |
16025513 | Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice. | 2005 Aug |
2 |
| 43 |
16317704 | Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappab to activate hepatic apoptosis in genetically obese mice. | 2005 Dec |
1 |
| 44 |
15205381 | Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from Cyp2e1(-/-) and wild-type mice. | 2004 Jul |
2 |
| 45 |
12085356 | Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage. | 2002 Jul |
1 |
| 46 |
11164737 | Regulation of peroxisome proliferator activated receptor alpha-mediated pathways in alcohol fed cytochrome P450 2E1 deficient mice. | 2001 Feb |
1 |
| 47 |
11032766 | Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in Cyp2e1(-/-) mice. | 2000 Oct 15 |
4 |
| 48 |
11180860 | Development of an intragastric enteral model in the mouse: studies of alcohol-induced liver disease using knockout technology. | 2000 |
1 |
| 49 |
9633991 | Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A. | 1998 May 15 |
4 |
| 50 |
7568332 | Cytochemical localization of the acetone-inducible cytochrome P-450 isoform, CYP2E1, in murine colonic epithelium. | 1995 Jun |
1 |