2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

midkine ; Mus musculus







183 Article(s)
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1 34645720 The expression of Annexin A1 and A5 mRNA by gonadotropin-releasing hormone in LβT2 gonadotrope cells. 2022 Mar 28 1
2 33239523 G protein-coupled receptor GPR151 is involved in trigeminal neuropathic pain through the induction of Gβγ/extracellular signal-regulated kinase-mediated neuroinflammation in the trigeminal ganglion. 2021 May 1 1
3 33369167 KLF4 down-regulation resulting from TLR4 promotion of ERK1/2 phosphorylation underpins inflammatory response in sepsis. 2021 Feb 1
4 34302803 Glycyrrhizic acid suppresses early stage of adipogenesis through repression of MEK/ERK-mediated C/EBPβ and C/EBPδ expression in 3T3-L1 cells. 2021 Sep 1 1
5 29018002 Glucose uptake inhibition decreases expressions of receptor activator of nuclear factor-kappa B ligand (RANKL) and osteocalcin in osteocytic MLO-Y4-A2 cells. 2018 Feb 1 1
6 29160030 Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARγ in 3T3-L1 cells. 2018 Feb 1
7 30191630 FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells. 2018 Nov 1
8 27864687 Omega-3 fatty acid EPA improves regenerative capacity of mouse skeletal muscle cells exposed to saturated fat and inflammation. 2017 Feb 1
9 27975141 Glucose and angiotensin II-derived endothelial extracellular vesicles regulate endothelial dysfunction via ERK1/2 activation. 2017 Feb 1
10 28034754 LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway. 2017 Jan 29 1
11 28057557 Anesthetics inhibit extracellular signal-regulated Kinase1/2 phosphorylation via NMDA receptor, phospholipase C and protein kinase C in mouse hippocampal slices. 2017 Feb 1
12 28190476 Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways. 2017 Feb 15 1
13 28405172 Mitogen-activated protein kinase phosphatase-3 (MKP-3) in the surgical wound is necessary for the resolution of postoperative pain in mice. 2017 1
14 28696542 (Pro)renin receptor activation increases profibrotic markers and fibroblast-like phenotype through MAPK-dependent ROS formation in mouse renal collecting duct cells. 2017 Nov 1
15 28867673 BMP7 dose-dependently stimulates proliferation and cadherin-11 expression via ERK and p38 in a murine metanephric mesenchymal cell line. 2017 Aug 1
16 29037608 Chemokine CCL8 and its receptor CCR5 in the spinal cord are involved in visceral pain induced by experimental colitis in mice. 2017 Oct 1
17 29075038 20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice. 2017 Oct 27 1
18 29270590 [Antioxidant effects of celastrol against hydrogen peroxide-induced oxidative stress in the cell model of amyotrophic lateral sclerosis]. 2017 Dec 25 1
19 26655082 Roles of NMDARs in maintenance of the mouse cerebrovascular endothelial cell-constructed tight junction barrier. 2016 Jan 2 1
20 26666965 Inhibition of macrophage-derived foam cell formation by ezetimibe via the caveolin-1/MAPK pathway. 2016 Feb 1
21 27248324 Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer. 2016 Jul 12 1
22 27401148 Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice. 2016 Jul 11 1
23 25814662 4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL. 2015 Jul 10 1
24 26101163 Melatonin attenuates hepatic ischemia through mitogen-activated protein kinase signaling. 2015 Sep 1
25 26388493 A novel natural product inspired scaffold with robust neurotrophic, neurogenic and neuroprotective action. 2015 Sep 21 2
26 24321770 Energy adaptive response during parthanatos is enhanced by PD98059 and involves mitochondrial function but not autophagy induction. 2014 Mar 1
27 24632067 Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells. 2014 Jun 2
28 24852102 Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2. 2014 Nov 1
29 25055824 Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. 2014 Sep 15 1
30 22714800 Angiotensin II suppresses adenosine monophosphate-activated protein kinase of podocytes via angiotensin II type 1 receptor and mitogen-activated protein kinase signaling. 2013 Feb 1
31 23415771 Pasteurella multocida toxin (PMT) upregulates CTGF which leads to mTORC1 activation in Swiss 3T3 cells. 2013 May 1
32 23556341 MMS 1001 inhibits melanin synthesis via ERK activation. 2013 Mar 1
33 23863460 Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice. 2013 Dec 1 2
34 23939027 Glial cell line-derived neurotrophic factor (GDNF) induced migration of spermatogonial cells in vitro via MEK and NF-kB pathways. 2013 Jul-Sep 1
35 24129178 Inhibition of melanogenesis by gallic acid: possible involvement of the PI3K/Akt, MEK/ERK and Wnt/β-catenin signaling pathways in B16F10 cells. 2013 Oct 14 1
36 22033125 Function of MAPK and downstream transcription factors in monomer-induced apoptosis. 2012 Jan 1
37 22131352 Knockdown of natriuretic peptide receptor-A enhances receptor C expression and signalling in vascular smooth muscle cells. 2012 Feb 1 1
38 22465219 Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway. 2012 Jul 1
39 22586143 ADAM10 promotes pituitary adenoma cell migration by regulating cleavage of CD44 and L1. 2012 Aug 1
40 22960610 Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model. 2012 Dec 1
41 24278749 SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes. 2012 1
42 20803555 CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts. 2011 Feb 1
43 21044800 Deficiency of SHP1 leads to sustained and increased ERK activation in mast cells, thereby inhibiting IL-3-dependent proliferation and cell death. 2011 Jan 1
44 21155602 A proteomic approach in investigating the hepatoprotective mechanism of Schisandrin B: role of raf kinase inhibitor protein. 2011 Jan 7 1
45 21325828 Differential role for ERK2 in anoxia-induced activation of transcription and translation of Hsp70 in NIH 3T3 cells. 2011 1
46 21668646 Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2α receptor mediated activation of MEK/ERK-CREB cascade. 2011 Aug 2
47 21691080 A semi-automated programme for tracking myoblast migration following mechanical damage: manipulation by chemical inhibitors. 2011 1
48 21745467 α₁-Adrenoceptor stimulation enhances leukemia inhibitory factor-induced proliferation of mouse-induced pluripotent stem cells. 2011 Oct 1 1
49 21778808 Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase. 2011 Oct 31 2
50 21816215 Partially purified components of Nardostachys chinensis suppress melanin synthesis through ERK and Akt signaling pathway with cAMP down-regulation in B16F10 cells. 2011 Oct 11 1