Title : Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways.

Pub. Date : 2017 Feb 15

PMID : 28190476






1 Functional Relationships(s)
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1 Blockade of PI3K/Akt or MEK/ERK signaling pathway by LY294002 or PD98059 could attenuate the increase of DA content in the striatum and TH-IR in the SNpc induced by icariin in PD mice model. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one midkine Mus musculus