Title : LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway.

Pub. Date : 2017 Jan 29

PMID : 28034754






1 Functional Relationships(s)
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1 Mechanistically, phosphorylation of MEK1/2 and ERK1/2 in NPCs was enhanced upon LXR agonist treatment, while abrogation of MEK/ERK phosphorylation by the inhibitors PD98059 and U0126 impaired the proliferation of wildtype NPCs in the presence or absence of LXR agonists. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one midkine Mus musculus