Tyrosine

spleen tyrosine kinase ; Mus musculus







80 Article(s)
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Pub. Year
#Total Relationships
51 15073337 The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase. 2004 Apr 20 1
52 15166239 Syk-mediated tyrosine phosphorylation is required for the association of hematopoietic lineage cell-specific protein 1 with lipid rafts and B cell antigen receptor signalosome complex. 2004 Aug 6 4
53 15265912 Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor. 2004 Aug 1 1
54 12586631 The carboxy-terminal region of the granulocyte colony-stimulating factor receptor transduces a phagocytic signal. 2003 Jun 1 2
55 12649157 Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation. 2003 Jul 15 1
56 12787756 Natural killer cell receptor signaling. 2003 Jun 1
57 14593208 Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. 2003 Nov 11 1
58 12470302 Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes. 2002 Dec 6 2
59 11207264 Antigen receptor proximal signaling in splenic B-2 cell subsets. 2001 Mar 1 2
60 10982358 The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo. 2000 Oct 1
61 10521450 Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt. 1999 Oct 22 2
62 10567557 LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. 1999 Dec 3
63 9531290 Activation of lyn, blk, and btk but not syk in CD72-stimulated B lymphocytes. 1998 Apr 1 1
64 9624175 Regulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinases. 1998 Jun 19 1
65 9632805 The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils. 1998 Jul 2
66 9782122 Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses. 1998 Oct 19 1
67 9036988 Increased secretion of TNF-alpha by costimulation of mast cells via CD28 and Fc epsilon RI. 1997 Mar 1 1
68 9079685 Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation. 1997 Mar 28 1
69 9171347 The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. 1997 May 1 3
70 9314552 A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. 1997 Oct 6 1
71 9324357 Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase. 1997 Sep 2
72 9346887 Syk and Fyn are required by mouse megakaryocytes for the rise in intracellular calcium induced by a collagen-related peptide. 1997 Oct 31 3
73 9396765 Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity. 1997 Dec 15 1
74 9464522 Activation of syk in an immature B cell line does not require lyn activity. 1997 Aug-Sep 1
75 8626447 Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase. 1996 Mar 15 3
76 7500027 Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling. 1995 Dec 1 5
77 7623809 Activation of the high-affinity immunoglobulin E receptor Fc epsilon RI in RBL-2H3 cells is inhibited by Syk SH2 domains. 1995 Aug 2
78 8720131 Phosphorylation of HS1, GAP-associated p190 and a novel GAP-associated p60 protein by cross-linking of Fc gamma RIIIA. 1995 Dec 1
79 7508923 Tyrosine phosphorylation of the gamma subunit of Fc gamma receptors, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages. 1994 Feb 4 1
80 7524079 Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. 1994 Sep 27 2