Title : A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages.

Pub. Date : 1997 Oct 6

PMID : 9314552






1 Functional Relationships(s)
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1 Macrophages derived from Syk-deficient (Syk-) mice were defective in phagocytosis of particles bound by FcgammaRs, as well as in many FcgammaR-induced signaling events, including tyrosine phosphorylation of a number of cellular substrates and activation of MAP kinases. Tyrosine spleen tyrosine kinase Mus musculus