| 1 |
35362478 | Tankyrase represses autoinflammation through the attenuation of TLR2 signaling. | 2022 Apr 1 |
2 |
| 2 |
34461100 | The receptor-type protein tyrosine phosphatase CD45 promotes onset and severity of IL-1β-mediated autoinflammatory osteomyelitis. | 2021 Oct |
2 |
| 3 |
31613396 | Alveolar Bone Protection by Targeting the SH3BP2-SYK Axis in Osteoclasts. | 2020 Feb |
1 |
| 4 |
31911307 | Design and optimization of orally spleen tyrosine kinase (SYK) inhibitors for treatment of solid tumor. | 2020 Jan |
1 |
| 5 |
32029896 | BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma. | 2020 Feb |
1 |
| 6 |
32040544 | Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived galectin-3. | 2020 Apr 2 |
1 |
| 7 |
31089414 | Syk and Hrs Regulate TLR3-Mediated Antiviral Response in Murine Astrocytes. | 2019 |
1 |
| 8 |
31545231 | MiR-377 mediates the expression of Syk to attenuate atherosclerosis lesion development in ApoE-/- mice. | 2019 Oct |
1 |
| 9 |
31780731 | The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation. | 2019 Nov 28 |
1 |
| 10 |
30541554 | Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation. | 2018 Dec 12 |
1 |
| 11 |
31249969 | TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists. | 2018 Oct |
1 |
| 12 |
28410990 | Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. | 2017 Apr 18 |
1 |
| 13 |
28705934 | Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets. | 2017 Sep 1 |
1 |
| 14 |
28716125 | Mercury alters endogenous phosphorylation profiles of SYK in murine B cells. | 2017 Jul 17 |
2 |
| 15 |
28760774 | Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation. | 2017 Nov 1 |
2 |
| 16 |
28768156 | The Syk kinases orchestrate cerebellar granule cell tangential migration. | 2017 Sep 30 |
1 |
| 17 |
29233969 | Receptor-interacting protein 140 as a co-repressor of Heat Shock Factor 1 regulates neuronal stress response. | 2017 Dec 12 |
1 |
| 18 |
27060497 | Down-modulation of antigen-induced activation of murine cultured mast cells sensitized with a highly cytokinergic IgE clone. | 2016 Jun |
1 |
| 19 |
27807193 | PTPN22 Is a Critical Regulator of Fcγ Receptor-Mediated Neutrophil Activation. | 2016 Dec 15 |
1 |
| 20 |
25520375 | Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis. | 2015 Feb 17 |
1 |
| 21 |
25645952 | Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation. | 2015 Jun |
1 |
| 22 |
25795918 | Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization. | 2015 Jun 25 |
2 |
| 23 |
26195794 | Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium. | 2015 Aug 4 |
1 |
| 24 |
24093153 | Reactive oxygen species play a critical role in collagen-induced platelet activation via SHP-2 oxidation. | 2014 Jun 1 |
2 |
| 25 |
24406398 | Tyrosine phosphorylation of 3BP2 is indispensable for the interaction with VAV3 in chicken DT40 cells. | 2014 Mar 10 |
1 |
| 26 |
23735482 | Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells. | 2013 Dec |
2 |
| 27 |
24023254 | The scaffold protein prohibitin is required for antigen-stimulated signaling in mast cells. | 2013 Sep 10 |
3 |
| 28 |
24386454 | Glaucocalyxin A inhibits platelet activation and thrombus formation preferentially via GPVI signaling pathway. | 2013 |
1 |
| 29 |
22019427 | The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2. | 2012 Feb |
1 |
| 30 |
22387094 | Arctigenin suppresses receptor activator of nuclear factor κB ligand (RANKL)-mediated osteoclast differentiation in bone marrow-derived macrophages. | 2012 May 5 |
1 |
| 31 |
21388954 | Syk regulates multiple signaling pathways leading to CX3CL1 chemotaxis in macrophages. | 2011 Apr 29 |
2 |
| 32 |
20004975 | Insulin potentiates FcepsilonRI-mediated signaling in mouse bone marrow-derived mast cells. | 2010 Feb |
1 |
| 33 |
20138367 | Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway. | 2010 Apr |
1 |
| 34 |
20167705 | Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways. | 2010 Apr 15 |
1 |
| 35 |
20194721 | Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts. | 2010 Apr 1 |
2 |
| 36 |
20639876 | Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. | 2010 Aug |
1 |
| 37 |
20851882 | The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival. | 2010 Nov 19 |
1 |
| 38 |
19219027 | Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. | 2009 Apr 16 |
1 |
| 39 |
19234161 | Bone marrow monocyte PECAM-1 deficiency elicits increased osteoclastogenesis resulting in trabecular bone loss. | 2009 Mar 1 |
1 |
| 40 |
19273622 | Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis. | 2009 Mar 16 |
1 |
| 41 |
19012179 | Hematopoietic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets. | 2008 Dec |
2 |
| 42 |
17353363 | Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. | 2007 Mar 12 |
1 |
| 43 |
17624942 | Convergence of immunoreceptor and integrin signaling. | 2007 Aug |
2 |
| 44 |
16291652 | Mutational analysis of the SH2-kinase linker region of Bruton's tyrosine kinase defines alternative modes of regulation for cytoplasmic tyrosine kinase families. | 2006 Jan |
1 |
| 45 |
16751367 | Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases. | 2006 Jun 15 |
3 |
| 46 |
17130299 | Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells. | 2006 Dec 25 |
3 |
| 47 |
15576379 | Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells. | 2005 Feb 11 |
3 |
| 48 |
15699129 | Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system. | 2005 Feb 15 |
1 |
| 49 |
16038788 | Mast cell activation is differentially affected by heat shock. | 2005 Aug |
2 |
| 50 |
14558887 | The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIa. | 2004 Feb 15 |
1 |