Title : Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells.

Pub. Date : 2006 Dec 25

PMID : 17130299






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Syk-transformed pre-B cells show a characteristic pattern of tyrosine phosphorylation, increased c-Myc expression, and defective differentiation. Tyrosine spleen tyrosine kinase Mus musculus
2 Treatment of Syk-transformed pre-B cells with a novel Syk-specific inhibitor (R406) reduces tyrosine phosphorylation and c-Myc expression. Tyrosine spleen tyrosine kinase Mus musculus
3 Treatment of Syk-transformed pre-B cells with a novel Syk-specific inhibitor (R406) reduces tyrosine phosphorylation and c-Myc expression. Tyrosine spleen tyrosine kinase Mus musculus