Pyruvaldehyde

glyoxalase 1 ; Mus musculus







67 Article(s)
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1 34710466 Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase. 2022 Jan 1 1
2 34838714 The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136. 2022 Jan 2
3 35500286 A ketogenic diet prevents methylglyoxal-evoked nociception by scavenging methylglyoxal. 2022 Apr 28 1
4 35620868 Glyoxalase 1 knockdown induces age-related β-cell dysfunction and glucose intolerance in mice. 2022 May 27 2
5 32678947 Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response. 2021 Mar 3
6 33917901 Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits. 2021 Apr 8 1
7 34516950 Metformin abrogates the voiding dysfunction induced by prolonged methylglyoxal intake. 2021 Nov 5 1
8 34669914 Eugenol and its liposome-based nano carrier reduce anxiety by inhibiting glyoxylase-1 expression in mice. 2021 4
9 31526867 Gene doubling increases glyoxalase 1 expression in RAGE knockout mice. 2020 Jan 2
10 31786717 Repeated Methylglyoxal Treatment Depletes Dopamine in the Prefrontal Cortex, and Causes Memory Impairment and Depressive-Like Behavior in Mice. 2020 Feb 1
11 31909963 Neural Glyoxalase Pathway Enhancement by Morin Derivatives in an Alzheimer's Disease Model. 2020 Feb 5 2
12 31968011 Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry. 2020 1
13 32298726 Long-term intake of the reactive metabolite methylglyoxal is not toxic in mice. 2020 Jul 2
14 32573222 Dietary Genistein Reduces Methylglyoxal and Advanced Glycation End Product Accumulation in Obese Mice Treated with High-Fat Diet. 2020 Jul 15 1
15 33166134 Glyoxalase 1 Inhibitor Alleviates Autism-like Phenotype in a Prenatal Valproic Acid-Induced Mouse Model. 2020 Nov 18 2
16 30342159 Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells. 2019 Jan 7
17 30508605 Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain. 2019 Jan 4
18 30628789 Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. 2019 Feb 14 1
19 30771486 SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary. 2019 Jun 1 2
20 30885990 Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes. 2019 Jun 4
21 30995106 Methylglyoxal triggers human aortic endothelial cell dysfunction via modulation of the KATP/MAPK pathway. 2019 Jul 1 1
22 31059718 Effect of dietary vitamin E on oxidative stress-related gene-mediated differences in anxiety-like behavior in inbred strains of mice. 2019 Aug 1 1
23 31370192 Therapeutic Potential of Lespedeza bicolor to Prevent Methylglyoxal-Induced Glucotoxicity in Familiar Diabetic Nephropathy. 2019 Jul 31 1
24 31557885 The Protective Effect of Brazilian Propolis against Glycation Stress in Mouse Skeletal Muscle. 2019 Sep 25 1
25 29495397 Eucommia ulmoides Ameliorates Glucotoxicity by Suppressing Advanced Glycation End-Products in Diabetic Mice Kidney. 2018 Feb 26 4
26 29532486 Glyoxalase 1 (GLO1) Inhibition or Genetic Overexpression Does Not Alter Ethanol's Locomotor Effects: Implications for GLO1 as a Therapeutic Target in Alcohol Use Disorders. 2018 May 5
27 29792365 Protective effects of piceatannol on methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells. 2018 Jun 1
28 30217477 Effects of methylglyoxal on RANKL-induced osteoclast differentiation in RAW264.7 cells. 2018 Dec 25 2
29 30287091 Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes. 2018 Dec 1
30 27864140 The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells. 2017 Feb 1
31 28170200 Glyoxalase-1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose-Derived Stem Cells in Streptozotocin-Induced Diabetic Mice Model of Critical Limb Ischemia. 2017 Jan 2
32 28623132 Generation and characterization of mouse knockout for glyoxalase 1. 2017 Aug 19 2
33 26670935 Glabridin Alleviates the Toxic Effects of Methylglyoxal on Osteoblastic MC3T3-E1 Cells by Increasing Expression of the Glyoxalase System and Nrf2/HO-1 Signaling and Protecting Mitochondrial Function. 2016 Jan 13 1
34 26711908 Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice. 2016 Mar 15 5
35 26788517 A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice. 2016 2
36 26956489 Methylglyoxal-Induced Endothelial Cell Loss and Inflammation Contribute to the Development of Diabetic Cardiomyopathy. 2016 Jun 4
37 27671893 Reappraisal of putative glyoxalase 1-deficient mouse and dicarbonyl stress on embryonic stem cells in vitro. 2016 Nov 15 1
38 25042521 Inhibitory effect of apocynin on methylglyoxal-mediated glycation in osteoblastic MC3T3-E1 cells. 2015 Apr 1
39 25387474 Increased peritoneal damage in glyoxalase 1 knock-down mice treated with peritoneal dialysis. 2015 Mar 4
40 26165190 Methylglyoxal, the foe and friend of glyoxalase and Trx/TrxR systems in HT22 nerve cells. 2015 Dec 1
41 24062246 Knockdown of glyoxalase 1 mimics diabetic nephropathy in nondiabetic mice. 2014 Jan 6
42 24164256 Methylglyoxal induces oxidative stress and mitochondrial dysfunction in osteoblastic MC3T3-E1 cells. 2014 Feb 1
43 24259499 Glyoxalase-1 overexpression in bone marrow cells reverses defective neovascularization in STZ-induced diabetic mice. 2014 Feb 1 3
44 24759959 Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo. 2014 Jul 1
45 24789098 Protective effect of liquiritigenin against methylglyoxal cytotoxicity in osteoblastic MC3T3-E1 cells. 2014 Jul 25 1
46 24812427 Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes. 2014 Nov 1
47 24920125 Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice. 2014 Jun 1 2
48 23409935 Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility. 2013 Apr 6
49 23797271 Aging-dependent reduction in glyoxalase 1 delays wound healing. 2013 5
50 24167592 Methylglyoxal evokes pain by stimulating TRPA1. 2013 4