Title : Repeated Methylglyoxal Treatment Depletes Dopamine in the Prefrontal Cortex, and Causes Memory Impairment and Depressive-Like Behavior in Mice.

Pub. Date : 2020 Feb

PMID : 31786717






1 Functional Relationships(s)
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1 An interesting finding was a marked decrease in dopamine levels in the prefrontal cortex of mice treated with 50 mg/kg MGO for 11 days, along with a ~ 25% decrease in the Glo1 content. Pyruvaldehyde glyoxalase 1 Mus musculus