| 1 |
33016182 | Identification of Compounds That Promote Readthrough of Premature Termination Codons in the CFTR. | 2021 Feb |
2 |
| 2 |
32499204 | Clinical effects of the three CFTR potentiator treatments curcumin, genistein and ivacaftor in patients with the CFTR-S1251N gating mutation. | 2020 Nov |
1 |
| 3 |
30841439 | Activation of constitutive androstane receptor inhibits intestinal CFTR-mediated chloride transport. | 2019 Mar |
1 |
| 4 |
30969810 | Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR. | 2019 Jul 1 |
1 |
| 5 |
30981209 | Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease. | 2019 Apr 12 |
5 |
| 6 |
26492939 | Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX-770 (ivacaftor). | 2016 Feb |
1 |
| 7 |
26863533 | Potentiation of ΔF508- and G551D-CFTR-Mediated Cl- Current by Novel Hydroxypyrazolines. | 2016 |
1 |
| 8 |
27160424 | Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations. | 2016 Sep |
7 |
| 9 |
27261451 | Personalized medicine in cystic fibrosis: genistein supplementation as a treatment option for patients with a rare S1045Y-CFTR mutation. | 2016 Aug 1 |
1 |
| 10 |
23827485 | Bronchorelaxation of the human bronchi by CFTR activators. | 2014 Feb |
1 |
| 11 |
24970923 | Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing. | 2014 Sep |
1 |
| 12 |
23343619 | Activation of AMP-activated protein kinase by a plant-derived dihydroisosteviol in human intestinal epithelial cell. | 2013 |
2 |
| 13 |
22302997 | Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation. | 2012 Jan 15 |
2 |
| 14 |
21441077 | Curcumin and genistein additively potentiate G551D-CFTR. | 2011 Jul |
4 |
| 15 |
21474426 | Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands. | 2011 Jul |
1 |
| 16 |
20023319 | Dynamic [Cl(-)](i) measurement with chloride sensing quantum dots nanosensor in epithelial cells. | 2010 Feb 5 |
1 |
| 17 |
20435887 | C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation. | 2010 Jul 16 |
1 |
| 18 |
20974851 | Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH. | 2010 Dec 31 |
1 |
| 19 |
19167254 | Molecular modeling of the heterodimer of human CFTR's nucleotide-binding domains using a protein-protein docking approach. | 2009 Apr |
1 |
| 20 |
18309088 | Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells. | 2008 Jun |
1 |
| 21 |
16798551 | Mutation specific therapy in CF. | 2006 |
1 |
| 22 |
15582996 | Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity. | 2005 Feb 18 |
1 |
| 23 |
15880796 | Pharmacological induction of CFTR function in patients with cystic fibrosis: mutation-specific therapy. | 2005 Sep |
1 |
| 24 |
15996659 | A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein. | 2005 Jul 18 |
1 |
| 25 |
16210354 | Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers. | 2005 Dec 1 |
1 |
| 26 |
12556293 | Effects of oral genistein in mice. | 2003 Mar-Apr |
1 |
| 27 |
14719993 | Pharmacological approaches to correcting the ion transport defect in cystic fibrosis. | 2003 |
1 |
| 28 |
12124395 | The cystic fibrosis mutation G551D alters the non-Michaelis-Menten behavior of the cystic fibrosis transmembrane conductance regulator (CFTR) channel and abolishes the inhibitory Genistein binding site. | 2002 Sep 27 |
5 |
| 29 |
12359632 | Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07. | 2002 Oct |
3 |
| 30 |
12386156 | Genistein improves regulatory interactions between G551D-cystic fibrosis transmembrane conductance regulator and the epithelial sodium channel in Xenopus oocytes. | 2002 Dec 27 |
1 |
| 31 |
11160632 | A common mechanism for cystic fibrosis transmembrane conductance regulator protein activation by genistein and benzimidazolone analogs. | 2001 Feb |
1 |
| 32 |
11262417 | Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. | 2001 Jun 8 |
3 |
| 33 |
11600438 | Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists. | 2001 Nov |
1 |
| 34 |
11703384 | Pharmacotherapy of the ion transport defect in cystic fibrosis. | 2001 Nov |
1 |
| 35 |
11845301 | Relationship between IkappaBalpha deficiency, NFkappaB activity and interleukin-8 production in CF human airway epithelial cells. | 2001 |
1 |
| 36 |
10766914 | Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line. | 2000 Apr 15 |
1 |
| 37 |
10829466 | [From the laboratory to the clinic: CFTR and the therapeutic options for cystic fibrosis]. | 2000 Feb |
1 |
| 38 |
10853862 | Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX. | 2000 May |
2 |
| 39 |
10898722 | Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole. | 2000 Jul |
4 |
| 40 |
10952679 | Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytes. | 2000 Aug |
3 |
| 41 |
10229679 | Inhibition of ATPase, GTPase and adenylate kinase activities of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator by genistein. | 1999 May 15 |
4 |
| 42 |
10519143 | The activation of an apical Cl- conductance by extracellular ATP is potentiated by genistein in Necturus gallbladder epithelium. | 1999 Sep |
1 |
| 43 |
9815107 | Flavonoids stimulate Cl conductance of human airway epithelium in vitro and in vivo. | 1998 Nov |
1 |
| 44 |
9142951 | cAMP and genistein stimulate HCO3- conductance through CFTR in human airway epithelia. | 1997 Apr |
3 |
| 45 |
9211816 | Direct action of genistein on CFTR. | 1997 Aug |
2 |
| 46 |
9277373 | Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanism. | 1997 Aug |
10 |
| 47 |
8772453 | Alternate stimulation of apical CFTR by genistein in epithelia. | 1996 Jan |
3 |
| 48 |
8572219 | Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers. | 1995 Dec |
2 |