Title : Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.

Pub. Date : 2002 Oct

PMID : 12359632






3 Functional Relationships(s)
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1 Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07. Genistein CF transmembrane conductance regulator Homo sapiens
2 The dose-dependence in G551D cells was shifted with respect to wild type CFTR so that higher genistein concentrations were required to observe activation and inhibition, respectively. Genistein CF transmembrane conductance regulator Homo sapiens
3 On human nasal epithelia the correction of G551D-CFTR defective conductance obtained with genistein was 20% that of wild type. Genistein CF transmembrane conductance regulator Homo sapiens