Pub. Date : 2019 Apr 12
PMID : 30981209
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease. | Genistein | CF transmembrane conductance regulator | Homo sapiens |
| 2 | Here, we evaluated the possibility that the over-the-counter nutraceutical genistein, known to potentiate CFTR function, would allow to control gliadin-induced alterations. | Genistein | CF transmembrane conductance regulator | Homo sapiens |
| 3 | We demonstrated that pre-treatment with genistein prevented P31-43-induced CFTR malfunction and an epithelial stress response in Caco-2 cells. | Genistein | CF transmembrane conductance regulator | Homo sapiens |
| 4 | These effects were abrogated when the CFTR gene was knocked out by CRISP/Cas9 technology, indicating that genistein protects intestinal epithelial cells by potentiating CFTR function. | Genistein | CF transmembrane conductance regulator | Homo sapiens |
| 5 | These effects were abrogated when the CFTR gene was knocked out by CRISP/Cas9 technology, indicating that genistein protects intestinal epithelial cells by potentiating CFTR function. | Genistein | CF transmembrane conductance regulator | Homo sapiens |