Serine

insulin receptor substrate 1 ; Homo sapiens







331 Article(s)
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1 34405431 Impaired brain insulin signalling in Parkinson's disease. 2022 Feb 1
2 35460012 Berberine Improves TNF-α-Induced Hepatic Insulin Resistance by Targeting MEKK1/MEK Pathway. 2022 Apr 22 2
3 35583807 The role of Pycnogenol in the control of inflammation and oxidative stress in chronic diseases: Molecular aspects. 2022 Jun 1
4 32536688 Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance. 2021 Sep 1
5 33173197 From population to neuron: exploring common mediators for metabolic problems and mental illnesses. 2021 Aug 1
6 33316649 Exploring brain insulin resistance in adults with bipolar depression using extracellular vesicles of neuronal origin. 2021 Jan 2
7 33433498 Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model. 2021 Aug 1
8 33648564 Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implications. 2021 Mar 1 2
9 33681196 Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats. 2021 1
10 33927970 Role of insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer's disease. 2021 Apr 1
11 34132491 Role of skeletal muscle lipids in the pathogenesis of insulin resistance of obesity and type 2 diabetes. 2021 Nov 4
12 31759099 Hepatic insulin resistance induced by mitochondrial oxidative stress can be ameliorated by sphingosine 1-phosphate. 2020 Feb 5 1
13 32383521 Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride-induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling. 2020 May 8 1
14 32580157 Short-chain fatty acids as novel therapeutics for gestational diabetes. 2020 Aug 1
15 32998286 Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling. 2020 Sep 28 2
16 33224105 Insulin Resistance at the Crossroad of Alzheimer Disease Pathology: A Review. 2020 1
17 30352252 Isomers of conjugated linoleic acid induce insulin resistance through a mechanism involving activation of protein kinase Cε in liver cells. 2019 Jan 1
18 30875909 Molecular Mechanisms of Hypothalamic Insulin Resistance. 2019 Mar 15 1
19 30964050 Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease. 2019 Aug 1
20 31223033 Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation. 2019 Jul 1
21 31426549 Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD. 2019 Aug 17 2
22 31461670 Cullin7 enhances resistance to trastuzumab therapy in Her2 positive breast cancer via degrading IRS-1 and downregulating IGFBP-3 to activate the PI3K/AKT pathway. 2019 Nov 1 1
23 29738527 Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models. 2018 2
24 29752419 Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance. 2018 May 11 1
25 30233499 Insulin Resistance in HIV-Patients: Causes and Consequences. 2018 2
26 30240640 Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase. 2018 Jul 27 4
27 30282066 Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus. 2018 2
28 30370665 Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals. 2018 Oct 2
29 30374127 Differential regulation of mTORC1 and mTORC2 is critical for 8-Br-cAMP-induced decidualization. 2018 Oct 30 3
30 30381640 [Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction]. 2018 2
31 30563117 Maternal Cognitive Impairment Associated with Gestational Diabetes Mellitus-A Review of Potential Contributing Mechanisms. 2018 Dec 5 1
32 27868170 Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance. 2017 Feb 1
33 27936435 Bilobalide abates inflammation, insulin resistance and secretion of angiogenic factors induced by hypoxia in 3T3-L1 adipocytes by controlling NF-κB and JNK activation. 2017 Jan 1
34 28011403 Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors. 2017 Mar 1
35 28161417 Celastrol attenuates mitochondrial dysfunction and inflammation in palmitate-mediated insulin resistance in C3A hepatocytes. 2017 Mar 15 1
36 28334990 Insulin resistance and exendin-4 treatment for multiple system atrophy. 2017 May 1 4
37 28380411 Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells. 2017 Jun 1
38 28393248 Epigallocatechin-3-gallate ameliorates insulin resistance in hepatocytes. 2017 Jun 1
39 28460125 How Protein Kinase A Activates Canonical Tyrosine Kinase Signaling Pathways To Promote Granulosa Cell Differentiation. 2017 Jul 1 8
40 28656239 Erythropoietin ameliorates PA-induced insulin resistance through the IRS/AKT/FOXO1 and GSK-3β signaling pathway, and inhibits the inflammatory response in HepG2 cells. 2017 Aug 1
41 28674284 C1qTNF-related protein 1 improve insulin resistance by reducing phosphorylation of serine 1101 in insulin receptor substrate 1. 2017 Aug 30 5
42 28684236 Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin. 2017 Oct 5 1
43 29027136 Oligonol promotes glucose uptake by modulating the insulin signaling pathway in insulin-resistant HepG2 cells via inhibiting protein tyrosine phosphatase 1B. 2017 Nov 1
44 26698173 Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE. 2016 Feb 5 2
45 26702053 Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation. 2016 Feb 26 2
46 26704265 Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes. 2016 Jan 15 4
47 26805878 Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells. 2016 Jan 21 2
48 26988763 Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity. 2016 May 15 2
49 27207509 Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes. 2016 Aug 1
50 27387397 Protective effects of marein on high glucose-induced glucose metabolic disorder in HepG2 cells. 2016 Aug 15 1