331 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
301 | 11287630 | A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. | 2001 Apr 10 | 3 |
302 | 11313980 | Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells. | 2001 Jan 25 | 4 |
303 | 11498541 | Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells. | 2001 Oct 12 | 1 |
304 | 11682617 | Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance. | 2001 Nov | 2 |
305 | 10764799 | Selective attenuation of metabolic branch of insulin receptor down-signaling by high glucose in a hepatoma cell line, HepG2 cells. | 2000 Jul 7 | 2 |
306 | 10781824 | Okadaic acid inhibits insulin-induced glucose transport in fetal brown adipocytes in an Akt-independent and protein kinase C zeta-dependent manner. | 2000 Apr 21 | 2 |
307 | 10830273 | Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes. | 2000 Jun | 4 |
308 | 10847581 | A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. | 2000 Jun | 3 |
309 | 10852715 | A single substitution of the insulin receptor kinase inhibits serine autophosphorylation in vitro: evidence for an interaction between the C-terminus and the activation loop. | 2000 Jun 20 | 1 |
310 | 10866039 | Serine residues 1177/78/82 of the insulin receptor are required for substrate phosphorylation but not autophosphorylation. | 2000 Jun | 1 |
311 | 11043572 | Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. | 2000 Oct | 5 |
312 | 10092613 | Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway. | 1999 Apr 2 | 5 |
313 | 10318852 | Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance. | 1999 May 14 | 1 |
314 | 10488146 | JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. | 1999 Sep 24 | 14 |
315 | 10497255 | Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. | 1999 Oct 1 | 5 |
316 | 9422753 | 14-3-3beta protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3'-kinase activity in 3T3L1 adipocytes. | 1998 Jan 9 | 2 |
317 | 9565570 | Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2. | 1998 May 8 | 1 |
318 | 9686926 | Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells). | 1998 Jul | 4 |
319 | 9761740 | Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase. | 1998 Oct 15 | 3 |
320 | 9832428 | Interaction of insulin receptor substrate-1 (IRS-1) with phosphatidylinositol 3-kinase: effect of substitution of serine for alanine in potential IRS-1 serine phosphorylation sites. | 1998 Dec | 9 |
321 | 9849961 | Insulin receptor substrate-1 and phosphatidylinositol 3-kinase regulate extracellular signal-regulated kinase-dependent and -independent signaling pathways during myogenic differentiation. | 1998 Dec | 3 |
322 | 9036989 | Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-alpha. | 1997 Mar 1 | 2 |
323 | 9312143 | 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. | 1997 Oct 3 | 6 |
324 | 9335553 | Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612. | 1997 Oct 21 | 2 |
325 | 9395471 | Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. | 1997 Dec 12 | 3 |
326 | 8626671 | Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action. | 1996 May 10 | 8 |
327 | 8660383 | Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells. | 1996 Jun 5 | 2 |
328 | 7818531 | The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes. | 1995 Jan 5 | 4 |
329 | 7998930 | Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase. | 1994 Nov 15 | 4 |
330 | 8119950 | Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. | 1994 Feb 25 | 5 |
331 | 8513971 | Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization. | 1993 Jul | 1 |