Title : Isomers of conjugated linoleic acid induce insulin resistance through a mechanism involving activation of protein kinase Cε in liver cells.

Pub. Date : 2019 Jan

PMID : 30352252






1 Functional Relationships(s)
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1 These findings indicate that cis-9, trans-11-CLA and trans-10, cis-12-CLA isomers could have a significant role in the development of insulin resistance in hepatic C9 cells through IRS-1 serine phosphorylation, PKCepsilon activation, and hepatic lipid accumulation. Serine insulin receptor substrate 1 Homo sapiens