BH 3

BCL2-associated X protein ; Mus musculus







14 Article(s)
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Pub. Year
#Total Relationships
1 27159560 Allosteric inhibition of antiapoptotic MCL-1. 2016 Jun 1
2 25715028 BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. 2015 1
3 25862283 Bcl-xL stimulates Bax relocation to mitochondria and primes cells to ABT-737. 2015 Jul 1
4 24352880 Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells. 2014 Feb 6 1
5 24227720 Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma. 2013 Nov 13 1
6 20503275 A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1. 2011 Apr 1 1
7 21199865 Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis. 2011 Mar 4 4
8 21247434 System in biology leading to cell pathology: stable protein-protein interactions after covalent modifications by small molecules or in transgenic cells. 2011 Jan 19 1
9 19816507 Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L). 2010 Feb 2
10 19951366 Pro-apoptotic activity of mBNIP-21 depends on its BNIP-2 and Cdc42GAP homology (BCH) domain and is enhanced by coxsackievirus B3 infection. 2010 May 1 2
11 21127253 BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program. 2010 Dec 3 1
12 17404107 Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1. 2007 Apr 1 1
13 17097561 The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. 2006 Nov 2
14 12624178 BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. 2003 Apr 4 1