Fatty Acids

peroxisome proliferator activated receptor alpha ; Homo sapiens







479 Article(s)
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1 34383332 Dispersion and utilization of lipid droplets mediates respiratory syncytial virus-induced airway hyperresponsiveness. 2022 Jan 1
2 34525916 Beneficial Effects of Dietary Polyphenols in the Prevention and Treatment of NAFLD: Cell-Signaling Pathways Underlying Health Effects. 2022 1
3 34687092 Perspectives in liver redox imbalance: Toxicological and pharmacological aspects underlying iron overloading, nonalcoholic fatty liver disease, and thyroid hormone action. 2022 Mar 1
4 34785106 Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury. 2022 Feb 1
5 35046108 Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation. 2022 May 4 1
6 35159062 A Double-Negative Feedback Interaction between miR-21 and PPAR-α in Clear Renal Cell Carcinoma. 2022 Feb 4 2
7 35325615 PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes. 2022 Apr 7 2
8 35396346 ROCK2-induced metabolic rewiring in diabetic podocytopathy. 2022 Apr 8 2
9 35460276 Intestinal peroxisome proliferator-activated receptor α-fatty acid-binding protein 1 axis modulates nonalcoholic steatohepatitis. 2022 Apr 23 1
10 35517820 Fatty Acid β-Oxidation in Kidney Diseases: Perspectives on Pathophysiological Mechanisms and Therapeutic Opportunities. 2022 1
11 35525025 Fatty acids derived from apoptotic chondrocytes fuel macrophages FAO through MSR1 for facilitating BMSCs osteogenic differentiation. 2022 Jul 2
12 35568871 SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism. 2022 May 14 1
13 35602098 A Molecular Insight into the Role of Antioxidants in Nonalcoholic Fatty Liver Diseases. 2022 2
14 35632821 Palmitoylethanolamide (PEA) Inhibits SARS-CoV-2 Entry by Interacting with S Protein and ACE-2 Receptor. 2022 May 17 1
15 32791172 The role of peroxisome proliferator-activated receptors (PPAR) in immune responses. 2021 Jan 1
16 33159388 MiR-22 modulates the expression of lipogenesis-related genes and promotes hepatic steatosis in vitro. 2021 Jan 1
17 33554726 Activation of Endogenous H2S Biosynthesis or Supplementation with Exogenous H2S Enhances Adipose Tissue Adipogenesis and Preserves Adipocyte Physiology in Humans. 2021 Aug 10 1
18 33578161 Exposure to short-chain chlorinated paraffins inhibited PPARα-mediated fatty acid oxidation and stimulated aerobic glycolysis in vitro in human cells. 2021 Jun 10 3
19 33580458 Evaluating the effect of a mixture of two main conjugated linoleic acid isomers on hepatic steatosis in HepG2 cellular model. 2021 Feb 1
20 33713839 Dual PPARγ/ɑ agonist oroxyloside suppresses cell cycle progression by glycolipid metabolism switch-mediated increase of reactive oxygen species levels. 2021 May 1 2
21 33719831 Peroxisome Proliferator-Activated Receptors (PPAR), fatty acids and microRNAs: Implications in women delivering low birth weight babies. 2021 Feb 1
22 33754023 Deficiency of telomere-associated repressor activator protein 1 precipitates cardiac aging in mice via p53/PPARα signaling. 2021 1
23 33801983 Lipidomics Provides New Insight into Pathogenesis and Therapeutic Targets of the Ischemia-Reperfusion Injury. 2021 Mar 10 1
24 33813326 Expression analysis of genes related to lipid metabolism in peripheral blood lymphocytes of chickens challenged with reticuloendotheliosis virus. 2021 May 2
25 33926085 The Role of Lipid Sensing Nuclear Receptors (PPARs and LXR) and Metabolic Lipases in Obesity, Diabetes and NAFLD. 2021 Apr 26 1
26 33946267 From Food to Genes: Transcriptional Regulation of Metabolism by Lipids and Carbohydrates. 2021 Apr 30 2
27 33981729 Resistin-Like Molecule α Dysregulates Cardiac Bioenergetics in Neonatal Rat Cardiomyocytes. 2021 1
28 34010603 The role of peroxisome proliferator-activated receptors in healthy and diseased eyes. 2021 Jul 1
29 34127848 PPAR control of metabolism and cardiovascular functions. 2021 Dec 1
30 34168538 Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation. 2021 1
31 34182904 Exploring dual agonists for PPARα/γ receptors using pharmacophore modeling, docking analysis and molecule dynamics simulation. 2021 Jun 28 1
32 34228977 Citrin deficiency: Does the reactivation of liver aralar-1 come into play and promote HCC development? 2021 Nov 1
33 34252412 Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet. 2021 Sep 1 1
34 34286232 Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes. 2021 Jul 23 1
35 34298981 PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming. 2021 Jul 8 2
36 34359615 Primary Aldosteronism: Metabolic Reprogramming and the Pathogenesis of Aldosterone-Producing Adenomas. 2021 Jul 23 1
37 34445261 The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance. 2021 Aug 9 1
38 34445672 Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα. 2021 Aug 20 1
39 34471048 Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR)α Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. 2021 1
40 34480827 PPARα at the crossroad of metabolic-immune regulation in cancer. 2021 Sep 4 1
41 34505013 Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9+ hepatocyte fate. 2021 Sep 24 1
42 34664288 Sesamol ameliorates hepatic lipid accumulation and oxidative stress in steatosis HepG2 cells via the PPAR signaling pathway. 2021 Nov 1
43 34768927 Gene Doping with Peroxisome-Proliferator-Activated Receptor Beta/Delta Agonists Alters Immunity but Exercise Training Mitigates the Detection of Effects in Blood Samples. 2021 Oct 25 1
44 34867358 (+)-Dehydrovomifoliol Alleviates Oleic Acid-Induced Lipid Accumulation in HepG2 Cells via the PPARα-FGF21 Pathway. 2021 1
45 30898012 Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model. 2020 Jan 3
46 31403341 PPAR Receptors Expressed from Vectors Containing CMV Promoter Can Enhance Self-Transcription in the Presence of Fatty Acids from CLA-Enriched Egg Yolks-A Novel Method for Studies of PPAR Ligands. 2020 4
47 31589122 Natural Aldose Reductase Inhibitor: A Potential Therapeutic Agent for Non-alcoholic Fatty Liver Disease. 2020 1
48 31730885 In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease. 2020 Feb 1 2
49 31733829 Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury. 2020 Feb 4
50 31871304 The Peroxisome Proliferator-Activated Receptor (PPAR)-γ Antagonist 2-Chloro-5-Nitro-N-Phenylbenzamide (GW9662) Triggers Perilipin 2 Expression via PPARδ and Induces Lipogenesis and Triglyceride Accumulation in Human THP-1 Macrophages. 2020 Mar 1