Title : Citrin deficiency: Does the reactivation of liver aralar-1 come into play and promote HCC development?

Pub. Date : 2021 Nov

PMID : 34228977






1 Functional Relationships(s)
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1 In CD, as a result of PPARalpha down-regulation, liver mitochondrial fatty acid-derived acetyl-CoA would, like glucose-derived acetyl-CoA, be used for lipid anabolism and fuel nuclear acetylation events which might trigger aralar-1 re-activation as seen in non-CD HCC. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens