Vardenafil Dihydrochloride

phosphodiesterase 5A, cGMP-specific ; Mus musculus







22 Article(s)
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1 34875337 Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line. 2022 Feb 15 1
2 34944010 Vardenafil Activity in Lung Fibrosis and In Vitro Synergy with Nintedanib. 2021 Dec 11 1
3 32126313 Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: Evidence of osteoanabolic and osteoangiogenic effects of the drugs. 2020 Jun 1
4 32513693 Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass. 2020 Jun 23 2
5 32747447 Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells. 2020 Aug 25 3
6 28196856 Vardenafil reduces macrophage pro-inflammatory overresponses in cystic fibrosis through PDE5- and CFTR-dependent mechanisms. 2017 Jun 1 4
7 28414103 Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition. 2017 Sep 30 2
8 24270408 Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium. 2014 Mar 1
9 24290227 Evaluation of PET radioligands for in vivo visualization of phosphodiesterase 5 (PDE5). 2014 Feb 2
10 24593781 Vardenafil ameliorates immunologic- and non-immunologic-induced allergic reactions. 2014 Mar 3
11 23348740 67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis. 2013 Feb 1
12 24204804 Correction of chloride transport and mislocalization of CFTR protein by vardenafil in the gastrointestinal tract of cystic fibrosis mice. 2013 1
13 22270721 cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. 2012 Jan 22 1
14 22441938 PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells. 2012 Aug 1
15 23024633 PDE5 Inhibitors as Potential Tools in the Treatment of Cystic Fibrosis. 2012 1
16 20562123 Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice. 2011 Jan 2
17 21681286 Tadalafil alters energy metabolism in C2C12 skeletal muscle cells. 2011 1
18 20109548 Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF. 2010 May 2
19 20413734 A phosphodiesterase-5 inhibitor vardenafil enhances angiogenesis through a protein kinase G-dependent hypoxia-inducible factor-1/vascular endothelial growth factor pathway. 2010 Jul 1
20 20419092 Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models. 2010 Apr 19 1
21 20471953 Sildenafil promotes adipogenesis through a PKG pathway. 2010 Jun 11 1
22 19368809 Effects of the PDE5-inhibitor vardenafil in a mouse stroke model. 2009 Apr 10 1