Title : A phosphodiesterase-5 inhibitor vardenafil enhances angiogenesis through a protein kinase G-dependent hypoxia-inducible factor-1/vascular endothelial growth factor pathway.

Pub. Date : 2010 Jul

PMID : 20413734






1 Functional Relationships(s)
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1 METHODS AND RESULTS: Unilateral hindlimb ischemia was generated by resecting right femoral artery in wild-type C3H/He mice, treated with either vehicle or a PDE5 inhibitor vardenafil (10 mg/kg per day). Vardenafil Dihydrochloride phosphodiesterase 5A, cGMP-specific Mus musculus