Title : Vardenafil ameliorates immunologic- and non-immunologic-induced allergic reactions.

Pub. Date : 2014 Mar

PMID : 24593781






3 Functional Relationships(s)
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1 The protective efficacy of the selective PDE5 inhibitor vardenafil against mast-cell-mediated allergic reactions in murine models has been investigated. Vardenafil Dihydrochloride phosphodiesterase 5A, cGMP-specific Mus musculus
2 In conclusion, inhibition of PDE5 by vardenafil ameliorated immunologic and non-immunologic mast-cell-mediated allergic reactions and reduced histamine release, providing evidence for the potential anti-allergic properties of vardenafil. Vardenafil Dihydrochloride phosphodiesterase 5A, cGMP-specific Mus musculus
3 In conclusion, inhibition of PDE5 by vardenafil ameliorated immunologic and non-immunologic mast-cell-mediated allergic reactions and reduced histamine release, providing evidence for the potential anti-allergic properties of vardenafil. Vardenafil Dihydrochloride phosphodiesterase 5A, cGMP-specific Mus musculus