| 1 |
31045274 | Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation. | 2019 Aug |
1 |
| 2 |
30250647 | Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response. | 2018 Aug 31 |
1 |
| 3 |
28911822 | Structural insights of cyclin dependent kinases: Implications in design of selective inhibitors. | 2017 Dec 15 |
3 |
| 4 |
27259234 | A novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway. | 2016 Jul 5 |
1 |
| 5 |
27771926 | Potential Use of Flavopiridol in Treatment of Chronic Diseases. | 2016 |
1 |
| 6 |
23300027 | Predicting the impact of single-nucleotide polymorphisms in CDK2-flavopiridol complex by molecular dynamics analysis. | 2013 Jul |
4 |
| 7 |
21575631 | Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells. | 2011 Aug 1 |
1 |
| 8 |
19535344 | The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity. | 2009 Jul |
1 |
| 9 |
17123821 | Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues. | 2007 Jan 15 |
2 |
| 10 |
15689157 | Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin. | 2005 Feb 10 |
1 |
| 11 |
15818598 | Transactivation of cyclin E gene by EWS-Fli1 and antitumor effects of cyclin dependent kinase inhibitor on Ewing's family tumor cells. | 2005 Sep 1 |
1 |
| 12 |
16140252 | Ligand binding affinity determined by temperature-dependent circular dichroism: cyclin-dependent kinase 2 inhibitors. | 2005 Oct 15 |
1 |
| 13 |
15122251 | Bioluminescent imaging of Cdk2 inhibition in vivo. | 2004 Jun |
1 |
| 14 |
15185335 | Charge optimization of the interface between protein kinases and their ligands. | 2004 Aug |
2 |
| 15 |
15252147 | Transcriptional signature of flavopiridol-induced tumor cell death. | 2004 Jul |
1 |
| 16 |
12457721 | Flavopiridol, a cyclin dependent kinase (CDK) inhibitor, induces apoptosis by regulating Bcl-x in oral cancer cells. | 2003 Jan |
3 |
| 17 |
12533675 | Flavopiridol-induced apoptosis is mediated through up-regulation of E2F1 and repression of Mcl-1. | 2003 Jan |
1 |
| 18 |
12598612 | Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition. | 2003 Feb 15 |
1 |
| 19 |
12852762 | A computational model of binding thermodynamics: the design of cyclin-dependent kinase 2 inhibitors. | 2003 Jul 17 |
3 |
| 20 |
11792416 | Growth inhibition and apoptosis of myeloma cells by the CDK inhibitor flavopiridol. | 2002 Mar |
1 |
| 21 |
12054639 | Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol. | 2002 Apr 26 |
2 |
| 22 |
11562278 | Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents. | 2001 Oct |
1 |
| 23 |
10741717 | Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells. | 2000 Mar |
1 |
| 24 |
10454206 | Cyclin-dependent kinases: initial approaches to exploit a novel therapeutic target. | 1999 May-Jun |
1 |
| 25 |
10493518 | Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol. | 1999 Sep 15 |
2 |
| 26 |
16127615 | Small molecule anticancer drugs. | 1999 Jun |
1 |
| 27 |
9639406 | Cell cycle-independent induction of apoptosis by the anti-tumor drug Flavopiridol in endothelial cells. | 1998 Jul 3 |
1 |
| 28 |
9802881 | Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis. | 1998 Nov 1 |
1 |
| 29 |
18465538 | Flavopiridol Hoechst AG. | 1998 Jun |
1 |
| 30 |
8674031 | Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. | 1996 Jul 1 |
7 |
| 31 |
21541623 | Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy. | 1996 Dec |
1 |