Title : Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells.

Pub. Date : 2011 Aug 1

PMID : 21575631






1 Functional Relationships(s)
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Protein Name
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1 Knockdown of cyclin-A using small interfering RNA (siRNA), and inhibiting Cdk2 activity with flavopiridol, strikingly reduced S-phase arrest and apoptosis. alvocidib cyclin dependent kinase 2 Homo sapiens