Calcium

ORAI calcium release-activated calcium modulator 1 ; Homo sapiens







199 Article(s)
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1 34939697 ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway. 2022 Jan 1
2 35076181 Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth. 2022 Apr 1
3 35113933 Absence of association between host genetic mutations in the ORAI1 gene and COVID-19 fatality. 2022 2
4 35151050 Control of STIM and Orai function by post-translational modifications. 2022 May 2
5 35151051 CRACR2A associated immunodeficiency - the supporting factor takes center stage. 2022 May 2
6 35254656 PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation. 2022 May 1
7 35369318 Parathyroid Hormone Promotes Human Umbilical Vein Endothelial Cell Migration and Proliferation Through Orai1-Mediated Calcium Signaling. 2022 1
8 35392575 Melatonin Mediates Osteoblast Proliferation Through the STIM1/ORAI1 Pathway. 2022 2
9 35571434 Abnormal neutrophil polarization in chronic obstructive pulmonary disease and how cigarette smoke extracts attract neutrophils. 2022 Apr 2
10 35628366 Involvement of ORAI1/SOCE in Human AML Cell Lines and Primary Cells According to ABCB1 Activity, LSC Compartment and Potential Resistance to Ara-C Exposure. 2022 May 16 2
11 35636153 STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39. 2022 May 18 1
12 33127334 LPS-induced vein endothelial cell injury and acute lung injury have Btk and Orai 1 to regulate SOC-mediated calcium influx. 2021 Jan 2
13 33316586 Twisting gating residues in the Orai pore. 2021 Jan 1
14 33361160 CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions. 2021 Jan-Jun 1
15 33361541 Nootkatol prevents ultraviolet radiation-induced photoaging via ORAI1 and TRPV1 inhibition in melanocytes and keratinocytes. 2021 Jan 1 1
16 33473127 STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing. 2021 Jan 20 3
17 33713955 STIM1 Regulates Endothelial Calcium Overload and Cytokine Upregulation During Sepsis. 2021 Jul 2
18 33717700 Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K+ channels inhibition. 2021 3
19 33718371 Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy. 2021 1
20 33748129 SARAF and Orai1 Contribute to Endothelial Cell Activation and Angiogenesis. 2021 1
21 33798603 ORAI3 silencing alters cell proliferation and promotes mitotic catastrophe and apoptosis in pancreatic adenocarcinoma. 2021 Jun 1
22 33859065 Flos magnoliae constituent fargesin has an anti-allergic effect via ORAI1 channel inhibition. 2021 May 1 2
23 33937254 ORAI1 Ca2+ Channel as a Therapeutic Target in Pathological Vascular Remodelling. 2021 3
24 34054913 Association of CASR, CALCR, and ORAI1 Genes Polymorphisms With the Calcium Urolithiasis Development in Russian Population. 2021 2
25 34055617 Calcium Channel Protein ORAI1 Mediates TGF-β Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells. 2021 1
26 34155535 Stromal interaction molecule 1 (STIM1) knock down attenuates invasion and proliferation and enhances the expression of thyroid-specific proteins in human follicular thyroid cancer cells. 2021 Aug 2
27 34498097 Defects in the STIM1 SOARα2 domain affect multiple steps in the CRAC channel activation cascade. 2021 Oct 2
28 34601312 PIP2 and septin control STIM1/Orai1 assembly by regulating cytoskeletal remodeling via a CDC42-WASP/WAVE-ARP2/3 protein complex. 2021 Nov 1
29 34639190 Anti-Inflammatory Effect of Licochalcone A via Regulation of ORAI1 and K+ Channels in T-Lymphocytes. 2021 Oct 7 1
30 34685684 Apoptotic Cells Trigger Calcium Entry in Phagocytes by Inducing the Orai1-STIM1 Association. 2021 Oct 9 3
31 34800360 Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation. 2021 Dec 2 5
32 31228261 STIM calcium sensing and conformational change. 2020 May 1
33 31556856 Structural and Mechanistic Insights of CRAC Channel as a Drug Target in Autoimmune Disorder. 2020 3
34 31600783 Single-nucleotide polymorphisms in Orai1 associated with atopic dermatitis inhibit protein turnover, decrease calcium entry and disrupt calcium-dependent gene expression. 2020 Jul 21 7
35 31626806 Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain. 2020 Jan 17 1
36 31676354 The pancreas-specific form of secretory pathway calcium ATPase 2 regulates multiple pathways involved in calcium homeostasis. 2020 Jan 1
37 31736242 Impairment of mitochondrial unfolded protein response contribute to resistance declination of H2 O2 -induced injury in senescent MRC-5 cell model. 2020 Feb 3
38 31755615 Prostaglandin E2 receptor EP4 regulates cell migration through Orai1. 2020 Jan 1
39 31818466 Increased Confinement and Polydispersity of STIM1 and Orai1 after Ca2+ Store Depletion. 2020 Jan 7 7
40 31822631 Detecting single ORAI1 proteins within the plasma membrane reveals higher-order channel complexes. 2020 Jan 3 1
41 31831178 Reversal of phosphate-induced ORAI1 expression, store-operated Ca2+ entry and osteogenic signaling by MgCl2 in human aortic smooth muscle cells. 2020 Feb 26 3
42 31846645 Modulation of Orai1 by cationic peptides triggers their direct cytosolic uptake. 2020 Mar 1 2
43 31936855 Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle. 2020 Jan 10 2
44 31952901 Cylindrical spirals in two families: Clinical and genetic investigations. 2020 Feb 1
45 32011316 Calcium channel Orai1 promotes lymphocyte IL-17 expression and progressive kidney injury. 2020 Feb 3 1
46 32012922 Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration. 2020 Jan 28 1
47 32146159 TRPM7 activation potentiates SOCE in enamel cells but requires ORAI. 2020 May 1
48 32240745 The FcεRIβ homologue, MS4A4A, promotes FcεRI signal transduction and store-operated Ca2+ entry in human mast cells. 2020 Jul 2
49 32350310 The orphan solute carrier SLC10A7 is a novel negative regulator of intracellular calcium signaling. 2020 Apr 29 1
50 32531836 Tensile force transmitted through LFA-1 bonds mechanoregulate neutrophil inflammatory response. 2020 Dec 2