Calcium

ORAI calcium release-activated calcium modulator 1 ; Homo sapiens







199 Article(s)
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151 22031864 The serum- and glucocorticoid-inducible kinase 1 (SGK1) influences platelet calcium signaling and function by regulation of Orai1 expression in megakaryocytes. 2012 Jan 5 1
152 22144678 Control of type I interferon-induced cell death by Orai1-mediated calcium entry in T cells. 2012 Jan 27 1
153 22364775 Effects of rapamycin-induced oligomerization of parvalbumin, Stim1 and Orai1 in puncta formation. 2012 May 1
154 22451904 Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1). 2012 Apr 10 1
155 22495877 Human ether à-gogo K(+) channel 1 (hEag1) regulates MDA-MB-231 breast cancer cell migration through Orai1-dependent calcium entry. 2012 Dec 1
156 22506990 Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1. 2012 Jul 1 1
157 22534489 Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel. 2012 May 25 5
158 22547681 Growth inhibition by miR-519 via multiple p21-inducing pathways. 2012 Jul 1
159 22556336 Platelet-derived growth factor maintains stored calcium through a nonclustering Orai1 mechanism but evokes clustering if the endoplasmic reticulum is stressed by store depletion. 2012 Jun 22 6
160 22938798 Dystrophin/α1-syntrophin scaffold regulated PLC/PKC-dependent store-operated calcium entry in myotubes. 2012 Dec 1
161 23109337 Crystal structure of calmodulin binding domain of orai1 in complex with Ca2+ calmodulin displays a unique binding mode. 2012 Dec 14 1
162 23520759 [Calcium signaling in platelet activation]. 2012 Dec 1
163 21176846 The role of store-operated calcium influx in skeletal muscle signaling. 2011 May 1
164 21224390 ORAI1-mediated calcium influx in lactation and in breast cancer. 2011 Mar 6
165 21300876 ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis. 2011 Feb 22 2
166 21383014 A cytosolic STIM2 preprotein created by signal peptide inefficiency activates ORAI1 in a store-independent manner. 2011 May 6 1
167 21420116 A polymorphism of the ORAI1 gene is associated with the risk and recurrence of calcium nephrolithiasis. 2011 May 3
168 21441136 Orai1 and CRAC channel dependence of VEGF-activated Ca2+ entry and endothelial tube formation. 2011 May 13 8
169 21545575 Nanomolar potency and selectivity of a Ca²⁺ release-activated Ca²⁺ channel inhibitor against store-operated Ca²⁺ entry and migration of vascular smooth muscle cells. 2011 Sep 2
170 21713652 Regulators of Ca(2+) signaling in mast cells: potential targets for treatment of mast cell-related diseases? 2011 2
171 21782006 Orai1/CRACM1 overexpression suppresses cell proliferation via attenuation of the store-operated calcium influx-mediated signalling pathway in A549 lung cancer cells. 2011 Dec 4
172 21873556 Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways. 2011 Dec 1
173 21880262 [Immunodeficiencies and pathologies associated with mutations in STIM/ORAI, a membrane complex in the heart of calcium signalling]. 2011 Aug-Sep 4
174 21945734 Calcium entry via ORAI1 regulates glioblastoma cell proliferation and apoptosis. 2011 Dec 2
175 22084111 POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters. 2011 Nov 29 2
176 19965684 Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow. 2010 Jan 21 4
177 20103768 Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1. 2010 Jun 1
178 20172609 Differential roles of STIM1, STIM2 and Orai1 in the control of cell proliferation and SOCE amplitude in HEK293 cells. 2010 Apr 2
179 20347143 The sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) is the third element in capacitative calcium entry. 2010 May 1
180 20546784 ORAI-mediated calcium entry: mechanism and roles, diseases and pharmacology. 2010 Aug 2
181 20729487 Pharmacology of store-operated calcium channels. 2010 Aug 1
182 20961852 Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells. 2010 Dec 24 3
183 21081754 Activation of STIM1-Orai1 involves an intramolecular switching mechanism. 2010 Nov 16 1
184 19088073 STIM1- and Orai1-dependent store-operated calcium entry regulates human myoblast differentiation. 2009 Feb 20 1
185 19088738 Calcium signaling in immune cells. 2009 Jan 1
186 19483082 Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides. 2009 Jul 31 3
187 19630797 Novel molecules in calcium signaling in platelets. 2009 Jul 1
188 19754895 Formation of STIM and Orai complexes: puncta and distal caps. 2009 Sep 1
189 18059270 Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. 2008 Jan 1
190 18187424 Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. 2008 Mar 21 6
191 18326500 Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels. 2008 May 9 1
192 17218358 Role of the store-operated calcium entry proteins Stim1 and Orai1 in muscarinic cholinergic receptor-stimulated calcium oscillations in human embryonic kidney cells. 2007 Mar 15 1
193 17224452 Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. 2007 Mar 23 1
194 17293345 Biochemical and functional characterization of Orai proteins. 2007 Jun 1 1
195 17343823 Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry. 2007 Apr 27 1
196 17360584 Orai proteins interact with TRPC channels and confer responsiveness to store depletion. 2007 Mar 13 1
197 17452328 Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels. 2007 Jun 15 1
198 16733527 Amplification of CRAC current by STIM1 and CRACM1 (Orai1). 2006 Jul 5
199 16807233 Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. 2006 Aug 25 2