Varenicline

cholinergic receptor nicotinic alpha 4 subunit ; Homo sapiens







37 Article(s)
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1 33977560 α4β2* Nicotinic Cholinergic Receptor Target Engagement in Parkinson Disease Gait-Balance Disorders. 2021 Jul 1
2 31096265 The Relationship of Varenicline Agonism of α4β2 Nicotinic Acetylcholine Receptors and Nicotine-Induced Dopamine Release in Nicotine-Dependent Humans. 2020 May 26 1
3 27805736 Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells. 2017 Jan 3
4 28268112 Taking varenicline for smoking cessation: A rare cause of pulmonary thromboembolism with infarction. 2017 Jul 7
5 28842382 Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor-mitogen activated protein kinase axis. 2017 Sep 1 1
6 29196725 Pharmacogenetic study of seven polymorphisms in three nicotinic acetylcholine receptor subunits in smoking-cessation therapies. 2017 Dec 1 1
7 27028298 Neuronal Nicotinic Acetylcholine Receptor Modulators Reduce Sugar Intake. 2016 3
8 27613505 Effects of varenicline on motor cortical plasticity in non-smokers with schizophrenia. 2016 Dec 1
9 25475645 Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes. 2015 Feb 2
10 25774163 CHRNA4 rs1044396 is associated with smoking cessation in varenicline therapy. 2015 2
11 24406270 Functional interactions of varenicline and nicotine with nAChR subtypes implicated in cardiovascular control. 2014 Jun 1
12 24627467 Activation of α4β2*/α6β2* nicotinic receptors alleviates anxiety during nicotine withdrawal without upregulating nicotinic receptors. 2014 May 2
13 24628360 Varenicline decreases ethanol intake and increases dopamine release via neuronal nicotinic acetylcholine receptors in the nucleus accumbens. 2014 Jul 2
14 24836728 Role for the nicotinic cholinergic system in movement disorders; therapeutic implications. 2014 Oct 1
15 25581658 Effects of varenicline on ethanol-induced conditioned place preference, locomotor stimulation, and sensitization. 2014 Dec 2
16 23042213 Modulation of α7 nicotinic acetylcholine receptor and fibrillar amyloid-β interactions in Alzheimer's disease brain. 2013 1
17 23110878 Individual differences in amygdala reactivity following nicotinic receptor stimulation in abstinent smokers. 2013 Feb 1 2
18 23641218 Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence. 2013 1
19 23801676 PET imaging of high-affinity α4β2 nicotinic acetylcholine receptors in humans with 18F-AZAN, a radioligand with optimal brain kinetics. 2013 Aug 1
20 22048466 Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. 2012 Feb 1
21 22395733 A single administration of low-dose varenicline saturates α4β2* nicotinic acetylcholine receptors in the human brain. 2012 Jun 2
22 22547331 Varenicline decreases alcohol consumption in heavy-drinking smokers. 2012 Oct 2
23 21097981 Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline. 2011 Jan 1
24 21368748 Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons. 2011 Jun 1
25 19959340 The nicotinic acetylcholine receptor partial agonist varenicline and the treatment of drug dependence: a review. 2010 Feb 3
26 20167427 Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain. 2010 Apr 1
27 20331614 Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence. 2010 May 1
28 20373480 Varenicline does not increase serum BDNF levels in patients with nicotine dependence. 2010 Apr 2
29 20946306 The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL/6J mice. 2010 Dec 3
30 19501054 Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition. 2009 Oct 1 3
31 19693492 Varenicline attenuates some of the subjective and physiological effects of intravenous nicotine in humans. 2009 Nov 2
32 20071853 Varenicline: for smoking cessation. 2009 Apr-Jun 2
33 18342165 Efficacy and safety of varenicline for smoking cessation. 2008 Apr 2
34 20040957 Partial nicotinic acetylcholine (alpha4beta2) agonists as promising new medications for smoking cessation. 2008 Oct 1
35 23506178 The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions. 2008 Sep 1
36 17353944 Varenicline: new treatment with efficacy in smoking cessation. 2007 Feb 3
37 15887955 Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. 2005 May 19 1