Title : Activation of α4β2*/α6β2* nicotinic receptors alleviates anxiety during nicotine withdrawal without upregulating nicotinic receptors.

Pub. Date : 2014 May

PMID : 24627467






2 Functional Relationships(s)
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1 Relative success in abstinence has been found with the nAChR partial agonist varenicline (Chantix; Pfizer, Groton, CT); however, treatment with this drug fails to alleviate anxiety in individuals during nicotine withdrawal. Varenicline cholinergic receptor nicotinic alpha 4 subunit Homo sapiens
2 Relative success in abstinence has been found with the nAChR partial agonist varenicline (Chantix; Pfizer, Groton, CT); however, treatment with this drug fails to alleviate anxiety in individuals during nicotine withdrawal. Varenicline cholinergic receptor nicotinic alpha 4 subunit Homo sapiens