Pub. Date : 2017 Jul
PMID : 28268112
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Varenicline (Champix , Chantix ) is a partial agonist of the alpha4beta2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the alpha7 nAChR. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 2 | Varenicline (Champix , Chantix ) is a partial agonist of the alpha4beta2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the alpha7 nAChR. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 3 | Varenicline (Champix , Chantix ) is a partial agonist of the alpha4beta2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the alpha7 nAChR. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 4 | Varenicline (Champix , Chantix ) is a partial agonist of the alpha4beta2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the alpha7 nAChR. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 5 | Varenicline (Champix , Chantix ) is a partial agonist of the alpha4beta2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the alpha7 nAChR. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 6 | Varenicline (Champix , Chantix ) is a partial agonist of the alpha4beta2 nicotinic acetylcholine receptor (nAChR) and a full agonist of the alpha7 nAChR. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |
| 7 | Varenicline has been associated with adverse cardiovascular (CV) events, including myocardial infarction, which may be caused by activation of the alpha7 nAChR receptor that in turn stimulates parasympathetic output from the brainstem to the heart, release of catecholamines, and has a prothrombotic effect. | Varenicline | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |