Iron

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







137 Article(s)
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1 34710708 Triad role of hepcidin, ferroportin, and Nrf2 in cardiac iron metabolism: From health to disease. 2022 Jan 2
2 35101526 COMMD10 inhibits HIF1α/CP loop to enhance ferroptosis and radiosensitivity by disrupting Cu-Fe balance in hepatocellular carcinoma. 2022 May 1
3 35173863 Deciphering the involvement of iron targets in colorectal cancer: a network biology approach. 2022 1
4 35192961 Comorbidity of osteoporosis and Alzheimer's disease: Is `AKT `-ing on cellular glucose uptake the missing link? 2022 Apr 1
5 35404886 The Role of Estrogen Signaling in Cellular Iron Metabolism in Pancreatic β Cells. 2022 Feb 1 2
6 32479616 Deferiprone Stimulates Aged Dermal Fibroblasts via HIF-1α Modulation. 2021 Mar 12 1
7 33932034 BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis. 2021 May 17 1
8 33969609 Lysosome Fe2+ release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells. 2021 Aug 1
9 34389031 Tumor cell-imposed iron restriction drives immunosuppressive polarization of tumor-associated macrophages. 2021 Aug 13 1
10 34714626 Kinetic Studies of the Hydrogen Atom Transfer in a Hypoxia-Sensing Enzyme, FIH-1: KIE and O2 Reactivity. 2021 Nov 9 2
11 31927949 Correction to Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1α Inhibitor Impairs Pancreatic Tumor Growth. 2020 Jan 28 1
12 32380365 Iron overload regulate the cytokine of mesenchymal stromal cells through ROS/HIF-1α pathway in Myelodysplastic syndromes. 2020 Apr 25 5
13 32420530 HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation. 2020 Mar 4 1
14 32477344 Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis. 2020 1
15 32541839 Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways. 2020 Jul 1
16 32881223 Ferric Ion Driven Assembly of Catalase-like Supramolecular Photosensitizing Nanozymes for Combating Hypoxic Tumors. 2020 Dec 14 2
17 30553971 Suppressive effects of iron chelation in clear cell renal cell carcinoma and their dependency on VHL inactivation. 2019 Mar 1
18 31672495 Relationships between hypoxia induced factor-1α and 18F-FDG PET/CT parameters in colorectal cancer. 2019 Nov - Dec 2
19 29318974 Understanding the Role of Hypoxia Inducible Factor During Neurodegeneration for New Therapeutics Opportunities. 2018 1
20 29580991 Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH. 2018 May 15 1
21 29764240 Ferrous glycinate regulates cell energy metabolism by restrictinghypoxia-induced factor-1α expression in human A549 cells. 2018 Dec 2
22 30148961 O2 Activation by Nonheme FeII α-Ketoglutarate-Dependent Enzyme Variants: Elucidating the Role of the Facial Triad Carboxylate in FIH. 2018 Sep 19 1
23 27848940 Parenteral iron polymaltose changes i:c-terminal FGF23 ratios in iron deficiency, but not in dialysis patients. 2017 Feb 1
24 28004401 Hypoxia-inducible factors as neuroprotective agent in Alzheimer's disease. 2017 Mar 1
25 28296633 The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels. 2017 Mar 15 1
26 28460338 Iron overload promotes erythroid apoptosis through regulating HIF-1a/ROS signaling pathway in patients with myelodysplastic syndrome. 2017 Jul 9
27 26818499 Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease. 2016 Jan 27 4
28 27449336 Local delivery of iron chelators reduces in vivo remodeling of a calcium phosphate bone graft substitute. 2016 Sep 15 2
29 24803010 Hypoxia-inducible factor-1α (HIF-1α) expression in placentae of women with iron deficiency anemia and β-thalassemia trait. 2015 Mar 1
30 25535360 Transdermal deferoxamine prevents pressure-induced diabetic ulcers. 2015 Jan 6 1
31 25727755 Iron Regulatory Protein 1 Suppresses Hypoxia-Induced Iron Uptake Proteins Expression and Decreases Iron Levels in HepG2 Cells. 2015 Sep 1
32 24161166 Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles. 2014 Jan 1
33 24397846 Iron chelation and multiple sclerosis. 2014 Jan 30 1
34 24495550 Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response. 2014 Apr 2
35 24732598 Deferoxamine promotes MDA-MB-231 cell migration and invasion through increased ROS-dependent HIF-1α accumulation. 2014 2
36 25587028 Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma. 2014 Dec 30 1
37 22710383 Hypoxia-inducible factor-1α (HIF-1α) potentiates β-cell survival after islet transplantation of human and mouse islets. 2013 1
38 23097160 Differential in vitro and cellular effects of iron chelators for hypoxia inducible factor hydroxylases. 2013 Apr 1
39 23160040 Insulin promotes iron uptake in human hepatic cell by regulating transferrin receptor-1 transcription mediated by hypoxia inducible factor-1. 2013 Feb 3
40 23598047 Deferoxamine expedites consolidation during mandibular distraction osteogenesis. 2013 Aug 1
41 23633457 Molecular pathways: Fumarate hydratase-deficient kidney cancer--targeting the Warburg effect in cancer. 2013 Jul 1 1
42 23640898 Each member of the poly-r(C)-binding protein 1 (PCBP) family exhibits iron chaperone activity toward ferritin. 2013 Jun 14 1
43 23709747 Hypoxia upregulates the gene expression of mitochondrial aconitase in prostate carcinoma cells. 2013 1
44 23787140 Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change. 2013 Sep 1
45 24120591 Hypoxia-inducible factor-1α(Pro-582-Ser) polymorphism prevents iron deprivation in healthy blood donors. 2013 Oct 2
46 24211145 Estrogen-dependent changes in serum iron levels as a translator of the adverse effects of estrogen during infection: a conceptual framework. 2013 Dec 2
47 21413014 Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90. 2012 Feb 1 1
48 22156453 Novel therapeutic approach for neurodegenerative pathologies: multitarget iron-chelating drugs regulating hypoxia-inducible factor 1 signal transduction pathway. 2012 3
49 22181812 Iron facilitator LS081 reduces hypoxia-inducible factor-1α protein and functions as anticancer agent in hepatocellular carcinoma. 2012 Apr 5
50 22198321 Hypoxic preconditioning increases iron transport rate in astrocytes. 2012 Apr 6