Title : Kinetic Studies of the Hydrogen Atom Transfer in a Hypoxia-Sensing Enzyme, FIH-1: KIE and O2 Reactivity.

Pub. Date : 2021 Nov 9

PMID : 34714626






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Central to cellular oxygen sensing is factor-inhibiting HIF-1alpha (FIH), an alpha-ketoglutarate (alphaKG)/non-heme iron(II)-dependent dioxygenase that hydroxylates a specific asparagine residue of hypoxia inducible factor-1alpha (HIF-1alpha). Iron hypoxia inducible factor 1 subunit alpha Homo sapiens
2 Central to cellular oxygen sensing is factor-inhibiting HIF-1alpha (FIH), an alpha-ketoglutarate (alphaKG)/non-heme iron(II)-dependent dioxygenase that hydroxylates a specific asparagine residue of hypoxia inducible factor-1alpha (HIF-1alpha). Iron hypoxia inducible factor 1 subunit alpha Homo sapiens