| 1 |
34995689 | Disruption of Hfe leads to skeletal muscle iron loading and reduction of hemoproteins involved in oxidative metabolism in a mouse model of hereditary hemochromatosis. | 2022 Mar |
1 |
| 2 |
35445828 | Reversal of genetic brain iron accumulation by N,N'-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice. | 2022 Jul |
1 |
| 3 |
32079697 | Macrophage-HFE controls iron metabolism and immune responses in aged mice. | 2021 Jan 1 |
1 |
| 4 |
33054105 | Cell-specific expression of <i>Hfe</i> determines the outcome of <i>Salmonella enterica</i> serovar Typhimurium infection in mice | 2021 Dec 1 |
8 |
| 5 |
33839281 | Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways. | 2021 Jul 1 |
1 |
| 6 |
34722560 | Hfe Gene Knock-Out in a Mouse Model of Hereditary Hemochromatosis Affects Bodily Iron Isotope Compositions. | 2021 |
4 |
| 7 |
34829689 | Dietary Iron Overload and Hfe-/- Related Hemochromatosis Alter Hepatic Mitochondrial Function. | 2021 Nov 16 |
2 |
| 8 |
31339576 | Transferrin and H-ferritin involvement in brain iron acquisition during postnatal development: impact of sex and genotype. | 2020 Feb |
3 |
| 9 |
31778583 | Endothelial Bone Morphogenetic Protein 2 (Bmp2) Knockout Exacerbates Hemochromatosis in Homeostatic Iron Regulator (Hfe) Knockout Mice but not Bmp6 Knockout Mice. | 2020 Aug |
1 |
| 10 |
32083318 | Critical role for iron accumulation in the pathogenesis of fibrotic lung disease. | 2020 May |
2 |
| 11 |
32108988 | Gnpat does not play an essential role in systemic iron homeostasis in murine model. | 2020 Apr |
1 |
| 12 |
32239172 | Hereditary hemochromatosis disrupts uric acid homeostasis and causes hyperuricemia via altered expression/activity of xanthine oxidase and ABCG2. | 2020 Apr 30 |
1 |
| 13 |
32380257 | Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice. | 2020 Aug |
3 |
| 14 |
32754933 | Iron promotes the clearance of α-synuclein: An Editorial for 'H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity" on page 177. | 2020 Sep |
3 |
| 15 |
32766721 | Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expression. | 2020 Aug 28 |
1 |
| 16 |
32861780 | HFE and ALK3 act in the same signaling pathway. | 2020 Nov 20 |
6 |
| 17 |
33148716 | ESAT-6 Protein of Mycobacterium tuberculosis Increases Holotransferrin-Mediated Iron Uptake in Macrophages by Downregulating Surface Hemochromatosis Protein HFE. | 2020 Dec 1 |
3 |
| 18 |
30277817 | Brain iron loading impairs DNA methylation and alters GABAergic function in mice. | 2019 Feb |
2 |
| 19 |
30538134 | Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load. | 2019 Jan 24 |
1 |
| 20 |
31132316 | Intracellular iron uptake is favored in Hfe-KO mouse primary chondrocytes mimicking an osteoarthritis-related phenotype. | 2019 Jul |
7 |
| 21 |
31188032 | Renal iron accelerates the progression of diabetic nephropathy in the HFE gene knockout mouse model of iron overload. | 2019 Aug 1 |
4 |
| 22 |
31442254 | Mouse models of hereditary hemochromatosis do not develop early liver fibrosis in response to a high fat diet. | 2019 |
2 |
| 23 |
31667458 | Despite Genetic Iron Overload, Hfe-Hemochromatosis Mice Do Not Show Bone Loss. | 2019 Sep |
1 |
| 24 |
31669736 | Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice. | 2019 Dec 15 |
3 |
| 25 |
31717526 | Mild Iron Overload as Seen in Individuals Homozygous for the Alpha-1 Antitrypsin Pi*Z Variant Does Not Promote Liver Fibrogenesis in HFE Knockout Mice. | 2019 Nov 9 |
2 |
| 26 |
28350201 | A role for sex and a common HFE gene variant in brain iron uptake. | 2018 Mar |
6 |
| 27 |
29113455 | HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models. | 2018 May 1 |
1 |
| 28 |
29315562 | HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity. | 2018 May |
1 |
| 29 |
29467298 | Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation. | 2018 Feb 21 |
1 |
| 30 |
29927322 | Liver HFE protein content is posttranscriptionally decreased in iron-deficient mice and rats. | 2018 Oct 1 |
3 |
| 31 |
30271947 | The hemochromatosis protein HFE signals predominantly via the BMP type I receptor ALK3 in vivo. | 2018 |
1 |
| 32 |
30479929 | Distinct Iron Deposition Profiles of Liver Zones in Various Models with Iron Homeostasis Disorders. | 2018 Nov |
1 |
| 33 |
27936457 | Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis. | 2017 Apr |
2 |
| 34 |
28202542 | Mössbauer Spectra of Mouse Hearts Reveal Age-dependent Changes in Mitochondrial and Ferritin Iron Levels. | 2017 Mar 31 |
1 |
| 35 |
28443246 | Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection. | 2017 |
8 |
| 36 |
28558947 | Hemochromatosis Protein (HFE) Knockout Mice As a Novel Model of Hemochromatosis: Implications for Study and Management of Iron-Overload Cardiomyopathy. | 2017 Jul |
1 |
| 37 |
28720890 | Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis. | 2017 Jul 18 |
1 |
| 38 |
26403062 | Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical stress. | 2016 Mar |
3 |
| 39 |
26406355 | Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin. | 2016 Jan |
3 |
| 40 |
26829642 | Decreased Bone Formation Explains Osteoporosis in a Genetic Mouse Model of Hemochromatosiss. | 2016 |
3 |
| 41 |
27354540 | Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. | 2016 Jun |
1 |
| 42 |
27500074 | Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases. | 2016 |
1 |
| 43 |
25403101 | A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. | 2015 Mar |
2 |
| 44 |
25427953 | Effects of strain and age on hepatic gene expression profiles in murine models of HFE-associated hereditary hemochromatosis. | 2015 Jan |
2 |
| 45 |
25608116 | HJV and HFE Play Distinct Roles in Regulating Hepcidin. | 2015 May 20 |
4 |
| 46 |
25609138 | Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin. | 2015 May |
6 |
| 47 |
26047483 | Iron homeostasis and its disruption in mouse lung in iron deficiency and overload. | 2015 Oct |
1 |
| 48 |
26456104 | HFE gene: Structure, function, mutations, and associated iron abnormalities. | 2015 Dec 15 |
5 |
| 49 |
24284962 | Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice. | 2014 Jan |
2 |
| 50 |
24658816 | The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice. | 2014 Jun |
1 |