Title : HFE and ALK3 act in the same signaling pathway.

Pub. Date : 2020 Nov 20

PMID : 32861780






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The most frequent mutation in Hfe leads to reduced hepcidin expression and thereby causes iron overload. Iron homeostatic iron regulator Mus musculus
2 HFE protein levels were increased in Alk3fl/fl;Alb-Cre mice compared to Alk3fl/fl mice, which was caused by iron overload - and not by Alk3 deficiency. Iron homeostatic iron regulator Mus musculus
3 HFE protein expression is induced by iron overload, which further emphasizes the iron sensing function of HFE. Iron homeostatic iron regulator Mus musculus
4 HFE protein expression is induced by iron overload, which further emphasizes the iron sensing function of HFE. Iron homeostatic iron regulator Mus musculus
5 HFE protein expression is induced by iron overload, which further emphasizes the iron sensing function of HFE. Iron homeostatic iron regulator Mus musculus
6 HFE protein expression is induced by iron overload, which further emphasizes the iron sensing function of HFE. Iron homeostatic iron regulator Mus musculus