Paclitaxel

signal transducer and activator of transcription 3 ; Homo sapiens







47 Article(s)
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1 34405891 Apatinib weakens resistance of gastric cancer cells to paclitaxel by suppressing JAK/STAT3 signaling pathway. 2022 Apr 1
2 35437787 Noncoding RNAs and their therapeutics in paclitaxel chemotherapy: Mechanisms of initiation, progression, and drug sensitivity. 2022 May 1
3 35440807 Exosomal PD-L1 confers chemoresistance and promotes tumorigenic properties in esophageal cancer cells via upregulating STAT3/miR-21. 2022 Apr 19 2
4 34116927 Acylglycerol kinase promotes paclitaxel resistance in nasopharyngeal carcinoma cells by regulating FOXM1 via the JAK2/STAT3 pathway. 2021 Dec 2
5 31778258 Targeted activation of Stat3 in combination with paclitaxel results in increased apoptosis in epithelial ovarian cancer cells and a reduced tumour burden. 2020 Jan 1
6 31901301 Retraction notice to "STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells" [GENE 584 (1) (2016) 75-82]. 2020 Mar 10 1
7 32080166 ID1 confers cancer cell chemoresistance through STAT3/ATF6-mediated induction of autophagy. 2020 Feb 20 1
8 32401925 Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway. 2020 1
9 32705214 A small molecule STAT3 inhibitor, LLL12, enhances cisplatin‑ and paclitaxel‑mediated inhibition of cell growth and migration in human ovarian cancer cells. 2020 Sep 4
10 33023532 TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells. 2020 Oct 6 1
11 30431082 ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel. 2019 Jan 3
12 30622051 MicroRNA-503-5p Inhibits the CD97-Mediated JAK2/STAT3 Pathway in Metastatic or Paclitaxel-Resistant Ovarian Cancer Cells. 2019 Feb 1
13 30866697 Dasatinib can enhance paclitaxel and gemcitabine inhibitory activity in human pancreatic cancer cells. 2019 1
14 31077613 Epigenetic inhibition of the tumor suppressor ARHI by light at night-induced circadian melatonin disruption mediates STAT3-driven paclitaxel resistance in breast cancer. 2019 Sep 10
15 31197964 Pectasol-C Modified Citrus Pectin targets Galectin-3-induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids. 2019 Aug 1
16 29324735 Influence of c-Src on hypoxic resistance to paclitaxel in human ovarian cancer cells and reversal of FV-429. 2018 Jan 11 1
17 29565447 CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway. 2018 May 1
18 29914005 Targeted regulationof STAT3 by miR-29a in mediating Taxol resistance of nasopharyngeal carcinoma cell line CNE-1. 2018 2
19 27435393 Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder. 2017 Jan 15 2
20 28178652 STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cells. 2017 Feb 28 2
21 28350087 Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727. 2017 Apr 6
22 28440494 Low-dose paclitaxel suppresses the induction of M2 macrophages in gastric cancer. 2017 Jun 1
23 28946186 Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway. 2017 Nov 3
24 29072615 The Novel Triazolonaphthalimide Derivative LSS-11 Synergizes the Anti-Proliferative Effect of Paclitaxel via STAT3-Dependent MDR1 and MRP1 Downregulation in Chemoresistant Lung Cancer Cells. 2017 Oct 26 1
25 26878391 MiR-125a promotes paclitaxel sensitivity in cervical cancer through altering STAT3 expression. 2016 Feb 15 2
26 26976343 RETRACTED: STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells. 2016 Jun 10 2
27 27159676 MiR-125a promotes paclitaxel sensitivity in cervical cancer through altering STAT3 expression. 2016 May 9 1
28 27779649 Effect of curcumin and paclitaxel on breast carcinogenesis. 2016 Dec 1
29 27845771 The Novel miR-9600 Suppresses Tumor Progression and Promotes Paclitaxel Sensitivity in Non-small-cell Lung Cancer Through Altering STAT3 Expression. 2016 Nov 15 2
30 25544427 Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells. 2015 Mar 3
31 26360705 Inhibition of JAK2 Reverses Paclitaxel Resistance in Human Ovarian Cancer Cells. 2015 Nov 1
32 24167124 Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy. 2014 Sep 1
33 24525192 Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3. 2014 Apr 25 1
34 24886434 Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden. 2014 May 6 4
35 22723956 miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. 2012 2
36 22847181 Mitochondrial uncoupling protein 2 regulates the effects of paclitaxel on Stat3 activation and cellular survival in lung cancer cells. 2012 Nov 7
37 22904633 PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells. 2012 1
38 21949561 STAT3 Inhibition by Microtubule-Targeted Drugs: Dual Molecular Effects of Chemotherapeutic Agents. 2011 Jan 1 8
39 20113523 MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol. 2010 Jan 31 3
40 20113836 Role of STAT3 decoy oligodeoxynucleotides on cell invasion and chemosensitivity in human epithelial ovarian cancer cells. 2010 Feb 1
41 20693278 Microtubule-targeted chemotherapeutic agents inhibit signal transducer and activator of transcription 3 (STAT3) signaling. 2010 Nov 5
42 21122157 Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells. 2010 Dec 2 1
43 18587580 CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells. 2009 Mar 1
44 19372587 ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells. 2009 Apr 3
45 19491198 Reciprocal effects of STAT5 and STAT3 in breast cancer. 2009 Jun 1
46 19623660 Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3. 2009 Nov 1 1
47 16951221 Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer. 2006 Sep 1 3