Tyrosine

Janus kinase 2 ; Rattus norvegicus







64 Article(s)
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1 33942213 Vitamin D protects glomerular mesangial cells from high glucose-induced injury by repressing JAK/STAT signaling. 2021 Jun 1
2 27068033 Particulate Matter Facilitates C6 Glioma Cells Activation and the Release of Inflammatory Factors Through MAPK and JAK2/STAT3 Pathways. 2016 Aug 1
3 22095528 Hypothalamic action of glutamate leads to body mass reduction through a mechanism partially dependent on JAK2. 2012 Apr 1
4 22749532 Emulsified isoflurane induces postconditioning against myocardial infarction via JAK-STAT pathway. 2012 Dec 4
5 21929289 PDGF-β receptor and PKC have no effect on angiotensin II-induced JAK2 and STAT1 phosphorylation in vascular smooth muscle cells under high glucose condition. 2011 Oct 2
6 18798867 High glucose attenuates VEGF expression in rat multipotent adult progenitor cells in association with inhibition of JAK2/STAT3 signalling. 2009 Sep 1
7 19063868 Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB. 2009 Feb 23 2
8 18611343 [Effects of fluvastatin on the expression of Janus kinase 2/signal transducers and activators of transcription (JAK/STAT) in glomerular mesangial cells under high concentration of glucose]. 2008 Jul 2
9 17229938 Defective insulin and acetylcholine induction of endothelial cell-nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats. 2007 Apr 2
10 17466927 Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells. 2007 May 1
11 16597920 Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca2+ and insulin secretion. 2006 Sep 2
12 15601621 Interleukin-6 increases rat metalloproteinase-13 gene expression through Janus kinase-2-mediated inhibition of serine/threonine phosphatase-2A. 2005 Apr 1
13 15644867 Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes. 2005 Jan 1
14 15761162 Cross-talk between the insulin and leptin signaling systems in rat hypothalamus. 2005 Jan 1
15 16138568 Caffeic acid inhibits vascular smooth muscle cell proliferation induced by angiotensin II in stroke-prone spontaneously hypertensive rats. 2005 Apr 1
16 16257270 Jak2 tyrosine kinase prevents angiotensin II-mediated inositol 1,4,5 trisphosphate receptor degradation. 2005 Nov 2
17 16297319 [Effect of losartan on expression of Janus kinase 2 and signal transducer and activator of transcription 3 in glomeruli of diabetic rats]. 2005 Nov 1
18 14722323 The neuroprotective effect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel alpha7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase. 2004 Apr 3
19 12504822 The functional role of the JAK-STAT pathway in post-infarction remodeling. 2003 Jan 1
20 12538627 Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways. 2003 Feb 1
21 12586763 Interaction of the growth hormone receptor with cytokine-induced Src homology domain 2 protein in rat adipocytes. 2003 Mar 2
22 12674509 Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver. 2003 Jan 4
23 12795614 Mitogen-induced activation of Na+/H+ exchange in vascular smooth muscle cells involves janus kinase 2 and Ca2+/calmodulin. 2003 Jun 17 1
24 12960006 The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance. 2003 Dec 1
25 14657181 Angiotensin II blocks nicotine-mediated neuroprotection against beta-amyloid (1-42) via activation of the tyrosine phosphatase SHP-1. 2003 Dec 3 2
26 11162585 Role of G beta-subunit in angiotensin II-type 1 receptor signaling. 2001 Jan 26 2
27 11231909 Reactive oxygen species regulate heat-shock protein 70 via the JAK/STAT pathway. 2001 Mar 2
28 11445068 Insulin modulates leptin-induced STAT3 activation in rat hypothalamus. 2001 Jul 6 1
29 11489940 Impaired JAK-STAT signal transduction contributes to growth hormone resistance in chronic uremia. 2001 Aug 1
30 11604224 Differential phosphorylation of Janus kinase 2, Stat5A and Stat5B in response to growth hormone in primary rat adipocytes. 2001 Oct 25 3
31 10809230 Involvement of JAK/STAT (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway. 2000 May 1
32 10830295 Thyrotropin modulates interferon-gamma-mediated intercellular adhesion molecule-1 gene expression by inhibiting Janus kinase-1 and signal transducer and activator of transcription-1 activation in thyroid cells. 2000 Jun 1
33 10856262 Cardiotrophin-1 increases angiotensinogen mRNA in rat cardiac myocytes through STAT3 : an autocrine loop for hypertrophy. 2000 Jun 1
34 10976913 Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B. 2000 Sep 1
35 11032244 Regulation of cardiac Jak-2 in animal models of insulin resistance. 2000 Jun 2
36 11064147 Activation of the Jak/Stat signal transduction pathway in GH-treated rat osteoblast-like cells in culture. 2000 Oct 25 2
37 9886807 Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues. 1999 Jan 2
38 9892011 Termination of growth hormone pulse-induced STAT5b signaling. 1999 Jan 3
39 10432321 Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells. 1999 Aug 15 3
40 10585879 Role of janus kinase-2 in insulin-mediated phosphorylation and inactivation of protein phosphatase-2A and its impact on upstream insulin signalling components. 1999 Dec 15 6
41 11601336 Epidermal growth factor receptor participates in growth hormone signaling pathway in cardiac myocytes of neonatal rat. 1999 Jun 1
42 9528967 Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. 1998 Apr 3
43 9602424 Angiotensin II activates Stat5 through Jak2 kinase in cardiac myocytes. 1998 Apr 2
44 9685210 In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2. 1998 Mar 16 1
45 9722518 Activation of the Janus kinase/signal transducer and activator of transcription pathway by osmotic shock. 1998 Sep 4 1
46 9790227 GH signalling in pancreatic beta-cells. 1998 Apr 1
47 9169451 Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway. 1997 Jun 6 2
48 9207201 Prolactin-mediated inhibition of 20alpha-hydroxysteroid dehydrogenase gene expression and the tyrosine kinase system. 1997 Jun 27 1
49 9287353 Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor. 1997 Sep 12 3
50 9299374 The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes. 1997 Sep 1