Celecoxib

prostaglandin-endoperoxide synthase 2 ; Rattus norvegicus







185 Article(s)
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1 35152673 [Mechanism study of the protective effects of selective cyclooxygenase-2 enzyme inhibitors on the liver of rats with type 2 diabetes mellitus combined with nonalcoholic steatohepatitis via Rho/ROCK pathway]. 2022 Jan 20 2
2 33184783 Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome. 2021 Apr 1
3 33377278 Angiotensin II receptor blockade alleviates calcineurin inhibitor nephrotoxicity by restoring cyclooxygenase 2 expression in kidney cortex. 2021 May 1
4 34145945 Inhibition of cyclooxygenase-2 enhanced intestinal epithelial homeostasis via suppressing β-catenin signalling pathway in experimental liver fibrosis. 2021 Aug 1
5 34333049 Neuroprotective effect of combined use of nicotine and celecoxib by inhibiting neuroinflammation in ischemic rats. 2021 Oct 2
6 34466385 Cyclooxygenase-2 regulates PTHrP transcription in human articular chondrocytes and is involved in the pathophysiology of osteoarthritis in rats. 2021 Sep 2
7 34546832 Low-dose cyclooxygenase-2 (COX-2) inhibitor celecoxib plays a protective role in the rat model of neonatal necrotizing enterocolitis. 2021 Dec 5
8 34584558 Anti-inflammation treatment for protection of hepatocytes and amelioration of hepatic fibrosis in rats. 2021 Nov 1
9 32162076 Regulation of liver regeneration by prostaglandin E2 and thromboxane A2 following partial hepatectomy in rats. 2020 Aug 2
10 32595753 Caulis Sargentodoxae Prescription Plays a Therapeutic Role with Decreased Inflammatory Cytokines in Peritoneal Fluid in the Rat Endometriosis Model. 2020 2
11 32762277 Targeted cyclooxygenase-2 inhibiting nanomedicine results in pain-relief and differential expression of the RNA transcriptome in the dorsal root ganglia of injured male rats. 2020 Jan-Dec 1
12 32821072 Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats. 2020 Jul 28 1
13 30658157 Upregulation of cystathionine-γ-lyase/hydrogen sulfide pathway underlies the celecoxib counteraction of cyclosporine-induced hypertension and renal insult in rats. 2019 Apr 2
14 29306822 Celecoxib, a cyclooxygenase-2 inhibitor, offers chemoprevention against reproductive and neurobehavioural abnormalities induced by atrazine in male Wistar rats. 2018 Mar 1
15 29425800 Influence of the selective COX-2 inhibitor celecoxib on sex differences in blood pressure and albuminuria in spontaneously hypertensive rats. 2018 Mar 2
16 29491208 Effects of the Nonsteroidal Anti-inflammatory Drug Celecoxib on Mitochondrial Function. 2018 2
17 29763644 Immunomodulatory effect of Celecoxib on HMGB1/TLR4 pathway in a recurrent seizures model in immature rats. 2018 Jul 5
18 30038293 Cyclooxygenase-2 up-regulates hepatic somatostatin receptor 2 expression. 2018 Jul 23 1
19 27287478 Hepatic radiofrequency ablation: markedly reduced systemic effects by modulating periablational inflammation via cyclooxygenase-2 inhibition. 2017 Mar 4
20 28370133 Isobolographic Analyses of Proglumide-Celecoxib Interaction in Rats with Painful Diabetic Neuropathy. 2017 Mar 1
21 28466254 Celecoxib Alleviates Memory Deficits by Downregulation of COX-2 Expression and Upregulation of the BDNF-TrkB Signaling Pathway in a Diabetic Rat Model. 2017 Jun 3
22 28935286 Mercury exposure induces proinflammatory enzymes in vascular fibroblasts. 2017 Nov - Dec 2
23 26728412 Retraction: Suppression of N-Methyl-N-nitrosourea/Testosterone-Induced Rat Prostate Cancer Growth by Celecoxib: Effects on Cyclooxygenase-2, Cell Cycle Regulation, and Apoptosis Mechanism(s). 2016 Jan 1 1
24 27039721 Expression Patterns of Cancer Stem Cell Markers During Specific Celecoxib Therapy in Multistep Rat Colon Carcinogenesis Bioassays. 2016 1
25 27056726 Inhibition of cyclooxygenase-2 alleviates liver cirrhosis via improvement of the dysfunctional gut-liver axis in rats. 2016 Jun 1 1
26 27078846 mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency. 2016 May 10 2
27 27165595 [Effects of cyclooxygenase-2 selective inhibitor celecoxib on the expression of major vault protein in rats with status epilepticus]. 2016 May 2
28 27380212 Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats. 2016 Oct 1
29 27776498 Cyclooxygenase-2 inhibitor celecoxib attenuates joint contracture following immobilization in rat knees. 2016 Oct 24 2
30 25779473 Assessment of the potential ototoxicity of high-dose celecoxib, a selective cyclooxygenase-2 inhibitor, in rats. 2015 Jun 3
31 25860026 Colonic delivery of celecoxib is a potential pharmaceutical strategy for repositioning the selective COX-2 inhibitor as an anti-colitic agent. 2015 Oct 1
32 26159203 A Cyclooxygenase-2 Inhibitor Reduces Vascular Wall Thickness and Ameliorates Cognitive Impairment in a Cerebral Small Vessel Diseases Rat Model. 2015 1
33 26251576 Celecoxib coupled to dextran via a glutamic acid linker yields a polymeric prodrug suitable for colonic delivery. 2015 1
34 26400540 Celecoxib or diclofenac hepatic status in the presence or absence of rebamipide. 2015 Sep 1
35 26807121 Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone. 2015 Nov 2
36 27747190 Formulation and Evaluation of Liposomes for Transdermal Delivery of Celecoxib. 2015 Feb 1
37 24087846 The effect of celecoxib administration on the healing and neovascularization of colonic anastomosis in rats. 2014 Jun 1
38 24462351 Colon-targeted celecoxib ameliorates TNBS-induced rat colitis: a potential pharmacologic mechanism and therapeutic advantages. 2014 Mar 5 2
39 24462674 Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-β1/IL-2/COX-2/endothelin ET(B) receptor cascade. 2014 Mar 1 6
40 24909904 Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytes. 2014 Nov 3
41 25047516 Cyclooxygenase 2 inhibitor celecoxib inhibits glutamate release by attenuating the PGE2/EP2 pathway in rat cerebral cortex endings. 2014 Oct 3
42 22168377 Celecoxib, a selective cyclooxygenase-2 inhibitor, lowers plasma cholesterol and attenuates hepatic lipid peroxidation during carbon-tetrachloride-associated hepatotoxicity in rats. 2013 Jan 2
43 23485816 Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats. 2013 Jun 14 2
44 23561827 Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide. 2013 Apr 5 3
45 23922700 Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis. 2013 2
46 23960285 Effects of a selective cyclooxygenase-2 inhibitor (celecoxib) on fracture healing in rats. 2013 Jul 1
47 24136226 The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. 2013 Oct 17 2
48 24308155 Enhancement of antitumor activity by combination of tumor lysate-pulsed dendritic cells and celecoxib in a rat glioma model. 2013 3
49 24503405 [The effects of cyclooxygenase-2 inhibitors on peritoneal lymphangiogenesis and peritoneal function in uremic rats]. 2013 Dec 1
50 22245539 Cytoprotective effect of nonsteroidal antiinflammatory drugs in rat brain slices subjected to reoxygenation after oxygen-glucose deprivation. 2012 Apr 11 2